NCT06962059Recruiting
Healthy Volunteers Study
Vaginal Metabolome Healthy Volunteers Study
Source: ClinicalTrials.gov · Last updated 5 Feb 2026
Brief summary (registry, in English)
The purpose of this study is to examine the role of the bacterial environments and metabolites in the early detection and prediction of ovarian cancer development. Vaginal swabs and stool samples will be collected from healthy volunteers, or those without a known ovarian cancer diagnosis or genetic ovarian cancer risk. These samples will be compared to samples from participants with increased cancer risk and ovarian cancer diagnoses.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 10 Apr 2025
- Start date
- 21 Apr 2025
- Primary completion date
- 15 Jan 2027
- Lead sponsor
- Abramson Cancer Center at Penn Medicine
- Diseases
- Ovarian cancer
- NCT number
- NCT06962059
What you commit to
- Study type: Observational
- Planned participants: 50
- From 21 Apr 2025 to the primary completion date, 15 Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Antibiotic use (1 month prior to providing sample)
Other illness
- genetic mutations which increase risk of ovarian cancer: BRCA1/2, BRIP1, PALB2, Lynch Syndrome (MLH1, MSH2/EPCAM, MSH6) and ATM
- prior cancer diagnosis
- prior cancer treatment
Other
- no genetic testing results or unknown genetic status
- HRT use
Who the study is looking for
- has ovaries
Age in the registry: 30 years to 50 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Abramson Cancer Center of the University of Pennsylvania Coordinator of this site? Confirm its status | Philadelphia | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.