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NCT06962072Recruiting

Outcomes Following Limb Sparing Surgery for Soft Tissue Sarcoma

Body Image, Health-related Quality of Life, and Function After Soft Tissue Sarcoma Resection

Source: ClinicalTrials.gov · Last updated 19 Dec 2025

Brief summary (registry, in English)

The goal of this study is to assess body image, health-related quality of life (QoL), and functioning (gait function, joint function, and walking ability) in patients after resection of localized soft tissue sarcoma (STS) of the extremities. A secondary objective is to assess the influence of different variables (e.g., radiotherapy, ethnicity, etc.) on body image, health-related QoL, and functioning. Patients who underwent a surgical resection at the Amsterdam UMC between 2010 and 2021 will be approached to participate in the study. Participants will complete four questionnaires and undergo a physical examination. Additionally, they will have a 3D gait analysis, a 6-minute walk test with gas analysis, and a muscle strength assessment. Furthermore, muscle volume change will be evaluated on pre- versus postoperative MRI scans.

Status (registry)
Recruiting
Study type
Observational
Enrollment
150 (estimated)
First submitted
28 Mar 2025
Start date
24 Apr 2025
Primary completion date
1 Jan 2028
Lead sponsor
Amsterdam UMC
Diseases
Sarcoma
NCT number
NCT06962072

What you commit to

  • Study type: Observational
  • Planned participants: 150
  • From 24 Apr 2025 to the primary completion date, 1 Jan 2028
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Patients who cannot maintain 6 minutes of walking will be excluded from the 6-minute walk test.

Who the study is looking for

  • Treated with surgical resection for primary non-metastatic extremity STS at the Amsterdam UMC between 2010-2021.
  • Being able to visit the Amsterdam UMC, location AMC once or twice.
  • Pregnant patients must agree to be scheduled 5 months after their pregnancy ends.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Amsterdam UMC
Coordinator of this site? Confirm its status
AmsterdamNetherlandsRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.