NCT06962592Recruiting
Mentor Moms+ Study
A Community-based Adaptation of a Peer-led Intervention to Address Alcohol Use and HIV Risk in Pregnant Women in South Africa (Mentor Moms+)
Source: ClinicalTrials.gov · Last updated 2 Jul 2026
Brief summary (registry, in English)
The goal of this study is to adapt an existing evidence based intervention for use in pregnant and lactating people (PLP) who use alcohol. Through the pilot RCT, we aim to understand if tailored intervention, Mentor Mothers+, is effective in reducing alcohol use (primary outcome) and improving antiretroviral (PrEP or ART) adherence (secondary outcomes) among pregnant and breastfeeding women living with and without HIV in a community heavily burdened by this syndemic. The investigators will conduct an pilot randomized control trial in 100 pregnant women, recruited during antenatal care (ANC) visits within the Saldanha Bay Municipality clinic in Cape Town, South Africa. The RCT will involve the delivery of brief, individual motivational interviewing sessions provided by trained mentor mothers from the community who are on either PrEP (living without HIV) or ART (living with HIV) and who stopped or reduced alcohol use during pregnancy. The enrolled participants will be followed for a 6-month period spanning both pregnancy and postpartum stages.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 8 Apr 2025
- Start date
- 1 Sept 2025
- Primary completion date
- 31 Aug 2027
- Lead sponsor
- University of California, Los Angeles
- Diseases
- HIV
- NCT number
- NCT06962592
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 1 Sept 2025 to the primary completion date, 31 Aug 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Individuals not meeting the above criteria will be excluded.
Who the study is looking for
- • ≥ 16 years;
- Pregnancy confirmed;
- reported alcohol use during pregnancy (in last 2 months);
- lives within 20 kilometers of the study facility;
- able and willing to consent to study participation.
Age in the registry: 16 years to - · Sex: Female · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Saldanha Bay Municipality Clinic Coordinator of this site? Confirm its status | Cape Town | South Africa | Not yet recruiting |
| Saldanha Bay Clinics Coordinator of this site? Confirm its status | Saldanha Bay | South Africa | Recruiting |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.