NCT06962644Recruiting
Association of Urinary Tract Infection With Preeclampsia During Pregnancy
Source: ClinicalTrials.gov · Last updated 8 May 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Urinary tract infections (UTIs) are a major clinical issue, especially in pregnant women, due to physiological changes that increase susceptibility. If untreated, UTIs can lead to severe complications like preterm labor and low birth weight. Preeclampsia, a hypertensive disorder affecting 0.2-9.2% of pregnancies, is another leading cause of maternal and fetal complications. The relationship between UTIs and preeclampsia remains controversial, with some studies suggesting an association while others show conflicting results. Research gaps highlight the need for region-specific studies, particularly in Pakistan, where both conditions contribute significantly to maternal and neonatal morbidity. This study aims to investigate the association between UTIs and preeclampsia in pregnant women in Pakistan. It will use a cohort design, enrolling 160 patients (80 with UTIs, 80 without) from the Obstetrics Department of PAF Hospital, Islamabad. Participants will be followed until delivery, with preeclampsia diagnosed based on blood pressure and proteinuria criteria. Data will be analyzed using SPSS to calculate relative risk (RR), with statistical significance set at RR \>1 and p ≤ 0.05. The findings could help improve prenatal care and reduce adverse outcomes in high-risk populations.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 160 (estimated)
- First submitted
- 22 Apr 2025
- Start date
- 1 Jan 2025
- Primary completion date
- 30 Apr 2025
- Lead sponsor
- Pakistan Air Force (PAF) Hospital Islamabad
- NCT number
- NCT06962644
What you commit to
- Study type: Observational
- Planned participants: 160
- From 1 Jan 2025 to the primary completion date, 30 Apr 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients on immunosuppressive therapy
Other illness
- History of medical conditions such as:
- Diabetes mellitus
- Chronic hypertension
- Chronic liver or kidney diseases
- Chronic pulmonary conditions
- History of urological surgical interventions in the past 3 months
- History of renal transplants
- History of comorbid conditions including:
- Diabetes mellitus
- Gestational diabetes mellitus
- Hypertension
- Chronic hepatic diseases
- Chronic liver diseases
- Chronic pulmonary diseases
- Ischemic heart diseases
Who the study is looking for
- Patients attending OPD for routine antenatal checkup
- Patients diagnosed with UTI as per operational definitions
- Gestational age greater than 20 weeks as per LMP
- Age between 18 to 35 years
Age in the registry: 18 years to 35 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| PAF Hospital, Islamabad Coordinator of this site? Confirm its status | Islamabad | Pakistan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.