Fact CheckerSign in

NCT06963385Active, not recruiting

Radiomics and Molecular Classification in Endometrial Cancer

Correlation Between RadiOmics and Molecular Classification in Endometrial Cancer (the ROME Study): a Step Forward to a Simplified Precision Medicine

Source: ClinicalTrials.gov · Last updated 9 May 2025

Brief summary (registry, in English)

Molecular/genomic profiling is the most accurate method to assess the prognosis of endometrial cancer patients. Interestingly, the adoption of radiomics showed important results, across various oncologic specialties. Radiomic allows extracting mineable high-dimensional data from clinical images, thus providing a number of noteworthy information of the tumor tissues. We aim to correlate radiomic features obtained from ultrasound images with the molecular/genomic profiling to identify new hallmarks for stratification of endometrial cancer patients into different classes of risk The central hypothesis is that combining radiomic features might allow identifying various classes of risk for endometrial cancer. The rationale for the proposed research is that once validated, radiomics applied to ultrasonographic images would be an effective, innovative, and cheap method for tailor operative and postoperative treatment modality in endometrial cancer.

Status (registry)
Active, not recruiting
Study type
Interventional
Enrollment
250 (estimated)
First submitted
1 Dec 2020
Start date
Jan 2021
Primary completion date
Dec 2026
Lead sponsor
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
NCT number
NCT06963385

What you commit to

  • Study type: Interventional
  • Planned participants: 250
  • From Jan 2021 to the primary completion date, Dec 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • (i) consent withdraw; (ii) lack of available (tumor) tissue for molecular/genomic profiling.

Who the study is looking for

  • (i) preoperative endometrial cancer (any histology); (ii) preoperative ultrasonographic examination; (iii) surgical treatment; (iv) age \>= 18 years; (v) signed informed consent for research purposes.

Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Fondazione IRCCS Istituto Nazionale dei Tumori di Milano
Coordinator of this site? Confirm its status
MilanItalyUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.