NCT06964919Completed
Research on Probiotics in Improving Obesity
Effectiveness and Safety of Inactivated Akkermansia Muciniphila Akk11 for Weight and Energy Metabolism in Obesity/Overweight: a Randomized, Double-blind, Placebo-controlled Trial
Source: ClinicalTrials.gov · Last updated 29 Jan 2026
Brief summary (registry, in English)
Assess the effects of Akkermansia muciniphila Akk11 heat - killed bacteria capsules compared to a placebo on body composition indicators (weight, BMI, body fat rate, waist - hip ratio (WC), wrist circumference, visceral fat area, basal metabolic rate) and blood lipid concentrations (total cholesterol (TC), low - density lipoprotein (LDL), high - density lipoprotein (HDL), triglycerides (TG)) in overweight/obese adults.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 61 (actual)
- First submitted
- 22 Apr 2025
- Start date
- 10 Mar 2025
- Primary completion date
- 30 Dec 2025
- Lead sponsor
- Wecare Probiotics Co., Ltd.
- Diseases
- Obesity
- NCT number
- NCT06964919
What you commit to
- Study type: Interventional
- Participants enrolled: 61
- From 10 Mar 2025 to the primary completion date, 30 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Presence of mental or neurological disorders, celiac disease, lactose intolerance, or allergies;
- Irritable Bowel Syndrome (IBS), Ulcerative Colitis, Hepatic Cirrhosis, or Diabetes Mellitus;
- Failure to consume the test product as required or attend follow-ups on time, making efficacy assessment impossible;
- Allergy to probiotic products;
Other
- Use of products similar to the test product in the near term that may affect the results;
- Pregnant, breastfeeding, or planning pregnancy;
- Antibiotic use within the past three months;
- Smoking more than 10 cigarettes a day;
- Other participants deemed unsuitable for the study by the investigator.
Who the study is looking for
- A body mass index (BMI) of ≥24 kg/m²;
- Willingness to provide written informed consent to participate in the study;
- Agreement to adhere to the study protocol and restrictions, including a low-carbohydrate, energy-restricted diet;
- No plans for conception from 14 days before screening until 6 months after the trial, with a commitment to using effective contraception.
Age in the registry: 18 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The School of Food and Bioengineering, Henan University of Science and Technolog Coordinator of this site? Confirm its status | Luoyang | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.