NCT06964932Completed
Probiotics in Obesity Management
Efficacy and Safety of Pasteurized Akkermansia Muciniphila Akk11 in Obesity/Overweight Weight Management and Energy Metabolism:a Randomized, Double-blind, Placebo-controlled Trial
Source: ClinicalTrials.gov · Last updated 18 Aug 2026
Brief summary (registry, in English)
Evaluate the effects of pasteurized Akkermansia muciniphila Akk11 (killed bacteria) capsules compared to placebo on body composition parameters (including weight, BMI, body fat percentage, waist - hip ratio (WHR), wrist circumference, visceral fat area, and basal metabolic rate) and blood lipid levels (total cholesterol (TC), low - density lipoprotein (LDL), high - density lipoprotein (HDL), and triglycerides (TG)) in overweight or obese adults.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 61 (actual)
- First submitted
- 22 Apr 2025
- Start date
- 25 Apr 2025
- Primary completion date
- 3 Dec 2025
- Lead sponsor
- Wecare Probiotics Co., Ltd.
- Diseases
- Obesity
- NCT number
- NCT06964932
What you commit to
- Study type: Interventional
- Participants enrolled: 61
- From 25 Apr 2025 to the primary completion date, 3 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Presence of mental or neurological disorders, celiac disease, lactose intolerance, or allergic conditions;
- Past diagnosis of Irritable Bowel Syndrome, Ulcerative Colitis, Hepatic Cirrhosis, or Diabetes Mellitus;
- Hypersensitivity to probiotic products;
Other
- Intake of products akin to the test product in the recent period that might sway the outcomes;
- Being pregnant, breastfeeding, or planning to conceive;
- Use of antibiotics in the preceding three months;
- Inability to comply with the test product regimen or attend follow-up visits regularly, making efficacy assessment unfeasible;
- Smoking in excess of 10 cigarettes daily;
- Any other participants deemed unsuitable for the research by the investigator.
Who the study is looking for
- A body mass index (BMI) of 24 kg/m² or above;
- Voluntarily signing an informed consent form to take part in the study;
- Willingness to undertake the study protocol and associated restrictions, such as adhering to a calorie - restricted - low carbohydrate diet;
- No intention to become pregnant from 14 days before screening, and commitment to using effective contraception until six months after the trial concludes.
Age in the registry: 18 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The School of Food and Bioengineering, Henan University of Science and Technolog Coordinator of this site? Confirm its status | Luoyang | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.