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NCT06966128Not yet recruiting

Transcranial Electrical Stimulation in Multiple Sclerosis

The Effect of Transcranial Direct Current Stimulation on Cerebral Blood Flow in Patients With Multiple Sclerosis

Source: ClinicalTrials.gov · Last updated 29 May 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

First the investigators will examine if the blood flow in the brain is different in patients with Multiple Sclerosis compared to healthy volunteers. HOW? \- The blood flow of the subjects is imaged by use of a special MRI-technique. Secondly, the investigators will examine if the blood flow can determine disease progression. HOW? - Multiple Sclerosis patients are asked for a follow-up visit after two years. The main goal is to understand the effect of transcranial Direct Current Stimulation (tDCS) on the cerebral blood flow. * Does tDCS result in a different blood flow, in which brain regions? * Is there a difference between healthy volunteers and Multiple Sclerosis patients? HOW? \- Participants get two session of tDCS. Before, during and after stimulation MRI scans are performed.

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
100 (estimated)
First submitted
6 Jan 2025
Start date
1 Jun 2025
Primary completion date
1 Jan 2029
Lead sponsor
Universitair Ziekenhuis Brussel
NCT number
NCT06966128

What you commit to

  • Study type: Interventional
  • Planned participants: 100
  • From 1 Jun 2025 to the primary completion date, 1 Jan 2029
  • 2 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Relapse within three months before the study and its use of corticosteroids
  • Disabling concomitant neuropsychiatric diseases
  • Disabling concomitant neuropsychiatric diseases

Other

  • EDSS \> 6.5
  • Incompatibility with MRI
  • Chance of pregnancy, breastfeeding
  • Contraindications to tDCS
  • Incompatibility with MRI
  • Chance of pregnancy, breastfeeding
  • Contraindications to tDCS

Who the study is looking for

  • EDSS ≥ 2 and EDSS ≤ 6.5
  • Age ≥ 18
  • Age ≥ 18

Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (2)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
University hospital of Brussels
Coordinator of this site? Confirm its status
BrusselsBelgiumUnknown status
National MS Center Melsbroek
Coordinator of this site? Confirm its status
MelsbroekBelgiumUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.