NCT06966128Not yet recruiting
Transcranial Electrical Stimulation in Multiple Sclerosis
The Effect of Transcranial Direct Current Stimulation on Cerebral Blood Flow in Patients With Multiple Sclerosis
Source: ClinicalTrials.gov · Last updated 29 May 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
First the investigators will examine if the blood flow in the brain is different in patients with Multiple Sclerosis compared to healthy volunteers. HOW? \- The blood flow of the subjects is imaged by use of a special MRI-technique. Secondly, the investigators will examine if the blood flow can determine disease progression. HOW? - Multiple Sclerosis patients are asked for a follow-up visit after two years. The main goal is to understand the effect of transcranial Direct Current Stimulation (tDCS) on the cerebral blood flow. * Does tDCS result in a different blood flow, in which brain regions? * Is there a difference between healthy volunteers and Multiple Sclerosis patients? HOW? \- Participants get two session of tDCS. Before, during and after stimulation MRI scans are performed.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 6 Jan 2025
- Start date
- 1 Jun 2025
- Primary completion date
- 1 Jan 2029
- Lead sponsor
- Universitair Ziekenhuis Brussel
- Diseases
- Multiple sclerosis
- NCT number
- NCT06966128
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 1 Jun 2025 to the primary completion date, 1 Jan 2029
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Relapse within three months before the study and its use of corticosteroids
- Disabling concomitant neuropsychiatric diseases
- Disabling concomitant neuropsychiatric diseases
Other
- EDSS \> 6.5
- Incompatibility with MRI
- Chance of pregnancy, breastfeeding
- Contraindications to tDCS
- Incompatibility with MRI
- Chance of pregnancy, breastfeeding
- Contraindications to tDCS
Who the study is looking for
- EDSS ≥ 2 and EDSS ≤ 6.5
- Age ≥ 18
- Age ≥ 18
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University hospital of Brussels Coordinator of this site? Confirm its status | Brussels | Belgium | Unknown status |
| National MS Center Melsbroek Coordinator of this site? Confirm its status | Melsbroek | Belgium | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.