NCT06967441Recruiting
Respiratory Virus Infections in Acute Heart Failure
Respiratory Virus Infections in Hospitalized Patients With Acute Heart Failure Syndrome: A Prospective Multi-center Observational Study
Source: ClinicalTrials.gov · Last updated 11 Mar 2026
Brief summary (registry, in English)
Patients admitted to the cardiology department with acute heart failure who have a nasopharyngeal respiratory virus PCR test performed within 72 hours of admission will be enrolled in the study cohort. The detection rate of respiratory viruses including influenza virus, RSV, and coronavirus will be analysed. The investigators will also look for seasonal changes in the frequency of respiratory viruses and differences in the clinical presentation of heart failure based on respiratory virus infection.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 360 (estimated)
- First submitted
- 17 Apr 2025
- Start date
- 7 Apr 2025
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- Minjae Yoon
- Diseases
- Heart failure
- NCT number
- NCT06967441
What you commit to
- Study type: Observational
- Planned participants: 360
- From 7 Apr 2025 to the primary completion date, 31 Dec 2028
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- If there is a clear other source of infection that can explain the fever
Lab values
- Patients with a clear other cause of acute heart failure (ex. ACS, bradycardia requiring a pacemaker, uncontrolled tachycardia, uncontrolled severe hypertension (SBP \>180mmHg or DBP \>110mmHg), haemoglobin \<7g/dL or AHF precipitated by medication non-adherence)
Other
- If the cause of pulmonary oedema is prominently attributed to exacerbation of CKD
Who the study is looking for
- Adult aged 19 years or older admitted to the cardiology department with acute heart failure
- NT-proBNP \>300 pg/mL
- Clinician judgement of possible respiratory viral infection (fever \>38 degrees or cough, respiratory symptoms such as sputum or consolidation on x-ray or CRP \>5 mg/dL)
- Patients who have a nasopharyngeal swab for respiratory virus PCR test performed within 72 hours of admission for any of the 3 reasons
Age in the registry: 19 years to - · Sex: All
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Seoul National University Bundang Hospital Coordinator of this site? Confirm its status | Seongnam-si | South Korea | Recruiting |
| Seoul St. Mary's Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Recruiting |
| Samsung Medical Center Coordinator of this site? Confirm its status | Seoul | South Korea | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.