NCT06967909Recruiting
Tai Chi and Acupuncture on Migraine Attack Prevention and Brain White Matter Changes
Effectiveness of Tai Chi and Acupuncture in the Prophylaxes of Episodic Migraine in Hong Kong Chinese Women and the Analysis of Microstructural White Matter Alterations: a Non-inferiority Single-blind Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 10 Sept 2026
Brief summary (registry, in English)
The goal of this clinical trial is to determine the effectiveness of Tai Chi training and acupuncture on the migraine attacks and structural brain changes in women with episodic migraine. Researchers will compare Tai Chi training to acupuncture treatment in a randomized controlled trial with 132 female participants. Participants will: * Be randomly assigned to either the Tai Chi group or the acupuncture group. * Undergo a 24-week intervention, with structured sessions for Tai Chi or scheduled acupuncture treatments. * Complete assessments through migraine diaries, questionnaires, physical measurements, MRI and TCD scans at various time points. The study ensures participant safety through close monitoring, with medical support available in case of discomfort. Data confidentiality will be maintained, with encrypted storage and restricted access for research purposes.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 132 (estimated)
- First submitted
- 5 May 2025
- Start date
- 1 Jan 2025
- Primary completion date
- 31 Oct 2026
- Lead sponsor
- The Hong Kong Polytechnic University
- Diseases
- Migraine
- NCT number
- NCT06967909
What you commit to
- Study type: Interventional
- Planned participants: 132
- From 1 Jan 2025 to the primary completion date, 31 Oct 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous practice of Tai Chi or other mind-body exercises (such as yoga, biofeedback, meditation, etc.);
- Received alternative treatments for migraines (such as acupuncture or Chinese medicine) during the recruitment period or within the past 12 weeks;
- Undergoing preventive medication treatment for migraines during the recruitment period or within the past 12 weeks;
- Pregnant, breastfeeding, or currently taking contraceptive medication.
Other illness
- Comorbid with other neurological disorders;
- Excessive use of medication, taking antipsychotic or antidepressant drugs, or using analgesics for other chronic pain conditions for more than 3 days per month within the past 12 weeks;
- Diagnosed with epilepsy or having a mental illness;
Other
- Unable to engage in moderate physical activity;
- Experiencing non-migraine headaches for more than 5 days per month;
Who the study is looking for
- Chinese women aged 18 years and above;
- Diagnosed with episodic migraines, with or without aura, according to the International Classification of Headache Disorders, 3rd edition (ICHD-3);
- Migraine attack frequency ranging from 2 to 14 days per month (≥15 days/month is classified as chronic migraine and is not included in this study);
- Assessed by a sports specialist as capable of engaging in moderate physical activity;
- Residing in Hong Kong.
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Hong Kong Polytechnic University Coordinator of this site? Confirm its status | Hung Hom | Hong Kong SAR China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.