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NCT06969573Active, not recruitingPhase 2

Inhaled Treprostinil for Dyspnea and Exercise Intolerance in Mild COPD

The Impact of Inhaled Treprostinil on Dyspnea and Exercise Intolerance in Mild COPD; a Pilot and Feasibility Trial

Source: ClinicalTrials.gov · Last updated 8 Jul 2026

Brief summary (registry, in English)

The goal of this clinical trial is to evaluate the impact of inhaled Treprostinil on breathlessness and low exercise capacity in patients living with mild chronic obstructive pulmonary disease. Participants will be asked to: * Perform lung function and exercise tests * Have ultrasound of their heart * Have CT images of their lungs * Visit the lab on 5 different occasions (plus one visit to the CT imaging clinic) The researchers will compare the effectiveness and feasibility of inhaled Treprostinil to improve breathlessness upon exertion and exercise capacity

Status (registry)
Active, not recruiting
Phase (registry)
Phase 2
Study type
Interventional
Enrollment
20 (actual)
First submitted
16 Apr 2025
Start date
5 Jun 2025
Primary completion date
31 Dec 2026
Lead sponsor
University of Alberta
Diseases
COPD
NCT number
NCT06969573

What you commit to

  • Study type: Interventional · Phase 2
  • Participants enrolled: 20
  • From 5 Jun 2025 to the primary completion date, 31 Dec 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Pre-existing heart failure and pulmonary artery hypertension.
  • Severe hepatic insufficiency

Other

  • Known thrombocytopenia.
  • Resting blood pressure of \<90mmHg systolic and \<50 mmHg diastolic.
  • Known sensitivity to prostanoids

Who the study is looking for

  • Patients with mild COPD (defined as having a postbronchodilator FEV1/FVC ratio \<0.70 and FEV1 ≥ 80% predicted

Age in the registry: 50 years to 85 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Clinical Physiology Laboratory
Coordinator of this site? Confirm its status
EdmontonCanadaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.