NCT06969768Completed
Proteogenomics for Follicular Cell-derived Thyroid Cancer: Development of a Classification and Prognosis Prediction Model
Integrative Multi-Omics Refines the Molecular Subtypes of Thyroid Cancers and Enhances Cancer-Progression Prediction
Source: ClinicalTrials.gov · Last updated 14 May 2025
Brief summary (registry, in English)
This study aims to refine the molecular classification of thyroid cancer (TC) using a multi-omics approach. By identifying a novel gene set and applying decision-tree modeling, the study seeks to improve diagnostic accuracy and predict tumor progression in BRAFV600E-like and RAS-like TC subtypes. Protein biomarkers were validated via immunohistochemistry (IHC), with findings confirmed across external datasets.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 275 (actual)
- First submitted
- 30 Apr 2025
- Start date
- 21 Feb 2018
- Primary completion date
- 21 Feb 2021
- Lead sponsor
- Seoul National University Hospital
- Diseases
- Thyroid cancer
- NCT number
- NCT06969768
What you commit to
- Study type: Observational
- Participants enrolled: 275
- From 21 Feb 2018 to the primary completion date, 21 Feb 2021
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- \- Patients who have received chemotherapy for other malignancies
Who the study is looking for
- Patients with a confirmed clinical diagnosis of thyroid cancer
- Availability of surgically resected thyroid tissue suitable for omics analysis
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Seoul National University Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.