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NCT06972277Completed

A Randomized Controlled Trial Comparing the Efficacy of Commercial Weight Management Programs

The Comparative Effectiveness of Commercial Weight Management Programs in Adults Living With Overweight or Obesity: A Randomized Controlled Trial

Source: ClinicalTrials.gov · Last updated 13 Apr 2026

Brief summary (registry, in English)

The study compares the effectiveness of three commercial weight management programs. The primary outcome is absolute and percentage weight change at 12-weeks.

Status (registry)
Completed
Study type
Interventional
Enrollment
459 (actual)
First submitted
6 May 2025
Start date
14 May 2025
Primary completion date
9 Jan 2026
Lead sponsor
WW International Inc
Diseases
Obesity
NCT number
NCT06972277

What you commit to

  • Study type: Interventional
  • Participants enrolled: 459
  • From 14 May 2025 to the primary completion date, 9 Jan 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Previous bariatric surgery or planned bariatric surgery during the study period
  • Major surgery within the past 6 months or plans to have surgery during the study period
  • Participation in the previous 3 months or current participation in a structured behavioral weight loss program
  • Current or previous history of anorexia or bulimia nervosa
  • Currently taking anti-obesity medications, planning to take anti-obesity medications in the next 6 months, or previously taken anti-obesity medications in the previous 3 months
  • Weight loss of ≥ 5 kg (11 lb) in the previous 6 months
  • History of heart problems (e.g., angina, bypass surgery, myocardial infarction, etc.) within previous 6 months

Other illness

  • Self-reported diagnosis of severe depression, bipolar disorder, substance abuse, or psychosis
  • Untreated thyroid disease or any changes (type or dose) in thyroid medication in last 6 months
  • Chronic/inflammatory gastrointestinal disorders (irritable bowel syndrome is acceptable)
  • Diagnosis of type 1 or type 2 diabetes
  • Presence of implanted cardiac defibrillator or pacemaker
  • History of cancer within past 5 years or current treatment for cancer
  • Hospitalization for psychiatric disorders during the last 12 months

Other

  • Pregnant, lactating, or plans to become pregnant in the next 6 months
  • Participation in another structured weight loss program during the study period (i.e., the next 3 months)
  • Communication needs that would render them unable to understand the study and/or intervention materials
  • Engagement with vomiting or laxative use within the last 28 days with the aim of controlling their shape or weight
  • Participants who are involved in any other research studies at this time

Who the study is looking for

  • 18 years or older
  • BMI ≥27 kg/m²
  • Own a bodyweight scale that they can weigh themselves with during the study
  • Willing and able to comply with study protocol
  • Capable of providing informed consent
  • Able to read and write in English
  • Willing to be randomized
  • Willing to sign a Non Disclosure Agreement

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
WW International, Inc
Coordinator of this site? Confirm its status
New YorkUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.