NCT06974994Recruiting
Resilience to Antibiotic-induced Obesogenic Microbiota: Discovering Mechanism of Microbiota Modulation
Resilience to Antibiotic-induced Obesogenic Microbiota Vertically Transferred to the Neonatal Gut: Discovering Mechanism of Microbiota Modulation
Source: ClinicalTrials.gov · Last updated 16 May 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The aim is to study whether the microbiota of children who are exposed to antibiotics at birth could be modified by synbiotic supplement and thereby reduce the risk of obesity, chronic diseases and respiratory tract infections. A total of 125 mother-child pairs will be recruited in this randomized, double-blind, placebo-controlled study. Infants are randomized to receive either a synbiotic supplement or a placebo for 2 months, after which their growth and morbidity will be monitored at the research clinic for 2 years.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 125 (estimated)
- First submitted
- 27 Apr 2025
- Start date
- 8 May 2024
- Primary completion date
- Dec 2029
- Lead sponsor
- Turku University Hospital
- Diseases
- Obesity
- NCT number
- NCT06974994
What you commit to
- Study type: Interventional
- Planned participants: 125
- From 8 May 2024 to the primary completion date, Dec 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Suspected malformation or serious condition of the foetus and neonates
- Serious infection or other conditions not permitting breast milk feeding
Other
- Chorioamnionitis
- Pre-eclampsia and hepatogestosis
Who the study is looking for
- Pregnant women (n=125) and their newborn children who receive antibiotic treatment at delivery.
Age in the registry: 2 hours to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Paediatrics and Adolescent Medicine, Turku University Hospital and University of Turku Coordinator of this site? Confirm its status | Turku | Finland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.