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NCT06977035Recruiting

Nerve Conduction Study for Assessment of Peripheral Neuropathy in Rheumatoid Arthritis Patients on the Janus Kinase Inhibitor Baricitinib

Source: ClinicalTrials.gov · Last updated 12 May 2026

Brief summary (registry, in English)

Rheumatoid arthritis is a chronic, systemic, autoimmune inflammatory disease that mainly affects the joints and periarticular soft tissues. Baricitinib (Olumiant®) is an oral, targeted synthetic DMARD that inhibits JAK1 and JAK2, which are implicated in the pathogenesis of rheumatoid arthritis (RA). Nerve conduction studies (NCSs) are an essential tool in the evaluation of the peripheral nervous system. The sensory nerve action potential (SNAP) provides information on the sensory nerve axon and its pathway from the distal receptors in the skin to the dorsal root ganglia, while the compound muscle action potential (CMAP) is an assessment of the motor nerve fibers from their origins in the anterior horn cell to their termination along muscle fibers.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
60 (estimated)
First submitted
24 Apr 2025
Start date
May 2025
Primary completion date
Nov 2025
Lead sponsor
Sohag University
NCT number
NCT06977035

What you commit to

  • Study type: Interventional
  • Planned participants: 60
  • From May 2025 to the primary completion date, Nov 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Other rheumatologic or collagen diseases.
  • Patients with other causes of peripheral neuropathy as Diabetes mellitus.

Age

  • Age below 18 years and above 65 years.

Other

  • Uncooperative patients.

Who the study is looking for

  • Patients fulfill the 2010 ACR/EULAR classification criteria of RA
  • Age above 18 years old.
  • Patient cooperative and can answer questions

Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Sohag University Hospital
Coordinator of this site? Confirm its status
SohagEgyptRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.