NCT06977035Recruiting
Nerve Conduction Study for Assessment of Peripheral Neuropathy in Rheumatoid Arthritis Patients on the Janus Kinase Inhibitor Baricitinib
Source: ClinicalTrials.gov · Last updated 12 May 2026
Brief summary (registry, in English)
Rheumatoid arthritis is a chronic, systemic, autoimmune inflammatory disease that mainly affects the joints and periarticular soft tissues. Baricitinib (Olumiant®) is an oral, targeted synthetic DMARD that inhibits JAK1 and JAK2, which are implicated in the pathogenesis of rheumatoid arthritis (RA). Nerve conduction studies (NCSs) are an essential tool in the evaluation of the peripheral nervous system. The sensory nerve action potential (SNAP) provides information on the sensory nerve axon and its pathway from the distal receptors in the skin to the dorsal root ganglia, while the compound muscle action potential (CMAP) is an assessment of the motor nerve fibers from their origins in the anterior horn cell to their termination along muscle fibers.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 24 Apr 2025
- Start date
- May 2025
- Primary completion date
- Nov 2025
- Lead sponsor
- Sohag University
- Diseases
- Rheumatoid arthritis
- NCT number
- NCT06977035
What you commit to
- Study type: Interventional
- Planned participants: 60
- From May 2025 to the primary completion date, Nov 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Other rheumatologic or collagen diseases.
- Patients with other causes of peripheral neuropathy as Diabetes mellitus.
Age
- Age below 18 years and above 65 years.
Other
- Uncooperative patients.
Who the study is looking for
- Patients fulfill the 2010 ACR/EULAR classification criteria of RA
- Age above 18 years old.
- Patient cooperative and can answer questions
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Sohag University Hospital Coordinator of this site? Confirm its status | Sohag | Egypt | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.