NCT06979752Recruiting
Efficacy and Safety of Tran Cannula in Combined Pseudoexfoliative Glaucoma and Cataract Surgery Compared With Augmented Ocular Irrigation
Source: ClinicalTrials.gov · Last updated 30 Sept 2026
Brief summary (registry, in English)
Pseudoexfoliative glaucoma is a glaucoma secondary to pseudoexfoliative syndrome; cataract surgery is often more difficult, with more complications. Tran's cannula is a single-use irrigation system designed for cleaning, with the pseudoexfoliative material remaining in the trabecular meshwork. The main objective of this study is to evaluate the efficacy of the Tran cannula, in comparison with increased irrigation, in lowering intraocular pressure (IOP) in patients with pseudoexfoliative glaucoma and treated for glaucoma, and with an indication for isolated cataract surgery.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 58 (estimated)
- First submitted
- 12 May 2025
- Start date
- 4 Jun 2025
- Primary completion date
- 2 Feb 2028
- Lead sponsor
- Hôpital Privé de la Baie
- Diseases
- Glaucoma
- NCT number
- NCT06979752
What you commit to
- Study type: Interventional
- Planned participants: 58
- From 4 Jun 2025 to the primary completion date, 2 Feb 2028
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- History of laser trabeculoplasty (TLA or SLT) in the previous 12 months
Other illness
- History of intraocular surgery in the last 12 months, history of trauma
- Pachymetry \< 490 μm or \> 620 μm; or corneal pathology or other condition that makes accurate IOP measurements with flattening tonometry, ultrasonic pachymetry or specular microscopy impossible.
Lab values
- Visual acuity below "finger count
Other
- Presence of other ophthalmological pathologies (except cataract or mild dry eye)
- Myopia ≥ 6 dioptres, hyperopia ≥ 5 dioptres
- Iridocorneal angle closure (and angle-closure glaucoma), any other type of non-pseudoexfoliative glaucoma, iris neovascularization
- Presence of severe systemic pathologies
Who the study is looking for
- Patients with cataract and early-to-moderate pseudoexfoliative glaucoma (GPX) scheduled for isolated cataract surgery.
- Reliable visual field, Humphrey 24-2, Sita-Fast, with typical glaucoma alterations, and with mean deviation ≤-12 dB.
- OCT with ganglion cell alterations and fibers typical of glaucoma.
- Typical glaucomatous neuropathy
- Slit-lamp signs of pseudoexfoliation.
- Open angle (2 to 4, according to Shaffer classification) determined by gonioscopy.
- Untreated eye pressure \>21 mmHg and \<33 mmHg
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hôpital Privé de la Baie Coordinator of this site? Confirm its status | Avranches | France | Recruiting |
| Fondation Rothschild Coordinator of this site? Confirm its status | Paris | France | Active, not recruiting |
| Clinique de la Côte d'Emeraude Coordinator of this site? Confirm its status | St-Malo | France | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.