NCT06983314Completed
Prescription Patterns of Antidepressants, Analgesics, and Antiepileptics Drugs in Adult With Acquired Brain Injury
Prescription Patterns of Antidepressants, Analgesics, and Antiepileptics Drugs in Adult Patients With Acquired Brain Injury Hospitalized in Rehabilitation Center Following Acute Care: a Bicentric Retrospective Study
Source: ClinicalTrials.gov · Last updated 21 May 2025
Brief summary (registry, in English)
Acquired brain injury (ABI), primarily caused by stroke and traumatic brain injury (TBI), leads to severe disabilities and requires complex pharmacological management during post-acute rehabilitation. The lack of dedicated guidelines and regular treatment re-evaluation increases the risk of adverse drug reactions (ADRs). Retrospective, bicentric study in two rehabilitation centers in Normandy, France, from November 1, 2020, to October 31, 2023, to describe prescription patterns of antidepressants, antiepileptics, and analgesics, as well as potential drug-related complications.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 201 (actual)
- First submitted
- 3 Feb 2025
- Start date
- 1 Nov 2020
- Primary completion date
- 31 Oct 2023
- Lead sponsor
- University Hospital, Caen
- Diseases
- Stroke
- NCT number
- NCT06983314
What you commit to
- Study type: Observational
- Participants enrolled: 201
- From 1 Nov 2020 to the primary completion date, 31 Oct 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who were already prescribed these drugs prior to the ABI.
Other
- Patients who did not receive new prescriptions for the pharmacological classes of interest during acute care or the first month of hospitalization in the rehabilitation center.
- Patients who were not hospitalized immediately after discharge from acute care (patients must have been transferred directly from acute care to the rehabilitation center, without spending time in another department or at home).
- Patients who were transferred to an emergency department during rehabilitation and did not return to the rehabilitation center.
- Patients who died during hospitalization or were discharged against medical advice.
Who the study is looking for
- Adults hospitalized in a rehabilitation center for acquired brain injury (ABI) after passing through an acute care department.
- ABI must be the primary diagnosis in the PMSI (French medical information system).
- The pharmacological classes of interest (antidepressants, antiepileptics, analgesics) must have been introduced during acute care or within the first month of hospitalization in the rehabilitation center.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU de Caen (Centre Hospitalier Universitaire de Caen, France) Coordinator of this site? Confirm its status | Caen | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.