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NCT06986083RecruitingPhase 3

A Study of Changes to Prostate Procedures

A Randomized Controlled Trial of Modifications to Prostate Needle-Based Procedures

Source: ClinicalTrials.gov · Last updated 15 Sept 2026

Brief summary (registry, in English)

The purpose of this study is to look whether using local anesthesia during a transperineal prostate biopsy, while put to sleep by IV sedation, helps reduce the number of people who feel significant pain in the recovery room. The researchers will also look at how local anesthesia affects the amount of pain medication used, how quickly people can go home after the biopsy, and how well they recover after leaving the hospital.

Status (registry)
Recruiting
Phase (registry)
Phase 3
Study type
Interventional
Enrollment
800 (estimated)
First submitted
20 May 2025
Start date
19 May 2025
Primary completion date
May 2028
Lead sponsor
Memorial Sloan Kettering Cancer Center
NCT number
NCT06986083

What you commit to

  • Study type: Interventional · Phase 3
  • Planned participants: 800
  • From 19 May 2025 to the primary completion date, May 2028
  • 7 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Local anesthesia versus no local anesthesia during transperineal biopsy, while patient is under IV sedation:
  • None
    • Standardization of a periprocedural pathway versus usual care for focal gland ablation:
  • None

Who the study is looking for

  • Local anesthesia versus no local anesthesia during transperineal biopsy, while the patient is under IV sedation:
  • Patients scheduled for transperineal prostate biopsy at the JRSC or Monmouth.
    • Standardization of a periprocedural pathway versus usual care for focal gland ablation:
  • Patients scheduled for a partial prostate gland ablation procedure at the JRSC.

Age in the registry: 18 years to - · Sex: Male · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (7)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Memorial Sloan Kettering Cancer Center at Basking Ridge (Consent Only)
Coordinator of this site? Confirm its status
Basking RidgeUnited StatesRecruiting
Memorial Sloan Kettering Suffolk - Commack (Consent Only)
Coordinator of this site? Confirm its status
CommackUnited StatesRecruiting
Memorial Sloan Kettering Westchester (Consent only)
Coordinator of this site? Confirm its status
HarrisonUnited StatesRecruiting
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
Coordinator of this site? Confirm its status
MiddletownUnited StatesRecruiting
Memorial Sloan Kettering Bergen (Consent Only)
Coordinator of this site? Confirm its status
MontvaleUnited StatesRecruiting
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
Coordinator of this site? Confirm its status
New YorkUnited StatesRecruiting
Memorial Sloan Kettering Nassau (Consent Only)
Coordinator of this site? Confirm its status
UniondaleUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.