NCT06986291Not yet recruiting
Radiation-induced Toxicity of the Heart
Quantitative Assessment of Radiation-induced Toxicity of the Heart
Source: ClinicalTrials.gov · Last updated 29 May 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Late side effects in radio(chemo)therapy \[R(CH)T\] pose a critical limitation to patients' overall survival and quality of life. Even though toxicities of the heart are highly relevant for patients with cancer in the thoracic region, risk stratification models for these toxicities are lacking. In this study, liquid, functional and imaging biomarkers are being investigated for their use in prediction of cardiac toxicity following R(CH)T for patients with thoracic malignancies.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 325 (estimated)
- First submitted
- 15 May 2025
- Start date
- Aug 2025
- Primary completion date
- Dec 2034
- Lead sponsor
- Technische Universität Dresden
- Diseases
- Lung cancer, Gastric and esophageal cancer
- NCT number
- NCT06986291
What you commit to
- Study type: Interventional
- Planned participants: 325
- From Aug 2025 to the primary completion date, Dec 2034
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with contraindications for MRI examinations (pacemakers, defibrillators, neurostimulators, aneurysm clips, cochlear implants, permanent make-up, metal splinters or osseosynthetic implants)
Lab values
- Patients with insufficient kidney function (glomerular filtration rate (GFR) of less than 30 ml/min)
Other
- Patients who are not capable of giving consent
- Pregnant women
- Patients with the aforementioned tumour entities for whom a palliative indication exists
Who the study is looking for
- Patients 18 years old or older
- Patient's consent and written consent is available
- Patients with the non-small cell lung cancer or esophageal cancer or breast cancer who have an indication for intended curative radio(chemo)therapy (in the case of breast cancer inclusion of female patients only)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Technology, University Hospital Carl Gustav Carus, Department of Radiation Therapy and Radiation Oncology Coordinator of this site? Confirm its status | Dresden | Germany | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.