NCT06987799Recruiting
Community-based Approach to Lowering Stress Through Mindfulness
Addressing Depression for African American Adults With Hypertension: Applying Community-Engaged Implementation Science
Source: ClinicalTrials.gov · Last updated 13 Apr 2026
Brief summary (registry, in English)
The goal of this clinical trial is to test a culturally adapted mindfulness-based stress reduction intervention in a community setting for African American adults with high blood pressure (hypertension) and depression. The main questions it aims to answer are: * Does participation in a culturally adapted mindfulness-based intervention improve depressive symptoms? * Does participation in a culturally adapted mindfulness-based intervention improve blood pressure control? * Is the intervention acceptable, appropriate, and feasible as delivered in a community setting? Participants will: * Participate in an 8-week group-based mindfulness intervention (CALM-Chicago). During intervention sessions, participants will learn about mindfulness and stress management and complete mindfulness-based activities, such as guided deep breathing and meditation. * Complete surveys online * Have their blood pressure measured with a non-invasive blood pressure cuff * Attend 1 focus group (optional)
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 5 May 2025
- Start date
- 10 Sept 2025
- Primary completion date
- 31 May 2028
- Lead sponsor
- Northwestern University
- Diseases
- High blood pressure
- NCT number
- NCT06987799
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 10 Sept 2025 to the primary completion date, 31 May 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Severe mental illness (e.g., bipolar disorder, psychosis)
Age
- \<18 years old
Other
- Current suicidal ideation (PHQ-9 item 9) or recent (past 6 months) suicide attempt
- Unable to provide informed consent or complete study activities in English
Who the study is looking for
- ≥18 years old
- Lives, works, or spends much of their time in the South Side of Chicago neighborhood
- Self-reports diagnosis of hypertension or high blood pressure by a clinician
- Endorses elevated depressive symptoms as Patient Health Questionnaire (PHQ)-9 scores ≥10
- Not taking antidepressant medication or stable on antidepressant medication for ≥6 months as self-reported
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Salvation Army Ray and Joan Kroc Corps Community Center Chicago Coordinator of this site? Confirm its status | Chicago | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.