NCT06992986Recruiting
Urinary Microbiome Differences in Bladder Cancer, Benign Urinary Diseases and Healthy Counterparts in Adult Male Population
Urinary Microbiome Differences in Bladder Cancer, Benign Urinary Diseases and Healthy Counterpars Adult Male Population: a Pilot Study
Source: ClinicalTrials.gov · Last updated 28 May 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The study aims to investigate alterations in the bladder microbiome in adult men with bladder cancer, healthy men, and men with benign urinary disease
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 18 Mar 2025
- Start date
- 6 Feb 2024
- Primary completion date
- 6 Jul 2025
- Lead sponsor
- Regina Elena Cancer Institute
- Diseases
- Bladder cancer
- NCT number
- NCT06992986
What you commit to
- Study type: Observational
- Planned participants: 50
- From 6 Feb 2024 to the primary completion date, 6 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- History of previous BCG therapy
- Active antibiotic treatment with two months prior to participation
- Previous neoadyuvant therapy
Other illness
- History of sexual transmitted diseases
- Diabetes
- Chronic Kidney Disease
- Cardiac disease
- Hepatic disease
Other
- Presence of other neoplasias
- Use of indwelling catheter
- Presence of chronic intestinal inflammation
- NA
Who the study is looking for
- Diagnosis of bladder cancer
- Negative urine culture
- Histological confirmation of urothelial carcinoma
- Patients undergoing radical cystectomy
- \- Controls will be collected from men within the specified age range. Eligible controls may be drawn from the institution's personnel attending the occupational medicine department or in service in the Institute.
- -To ensure that alterations in the microbiome observed in bladder cancer patients are unique to this condition, an additional group with benign urinary diseases will be included in the analysis. This group will encompass individuals with renal cysts, benign prostatic obstruction, ureteropelvic or ureteral obstruction undergoing surgical therapy.
Age in the registry: 50 years to 70 years · Sex: Male · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Regina Elena National Cancer Institute Coordinator of this site? Confirm its status | Rome | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.