NCT06995040Recruiting
BREMISS : Brain Resilience Minor Stroke Study
Initial Predictors of Long-term Brain Resilience After Minor Ischemic Stroke: a Study Nested in the Brest Stroke Population-based Registry
Source: ClinicalTrials.gov · Last updated 23 Feb 2026
Brief summary (registry, in English)
The objective of this clinical trial is to develop, based on patients' initial characteristics (in the first few weeks following the stroke), a predictive model of quality of life more than 4 years after the stroke in patients who have suffered a minor ischemic stroke. The main question it aims to answer is: \- Is it possible to predict the quality of life of patients who have suffered a minor ischemic stroke based on their initial characteristics? To do this, retrospective and prospective data collected as part of the study will be analyzed using a conventional statistical approach and algorithms based on AI approaches in order to create a predictive model. Participants will be asked to: * Complete questionnaires * Provide a saliva sample (optional) * Undergo an MRI scan (optional)
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 1000 (estimated)
- First submitted
- 21 May 2025
- Start date
- Jun 2025
- Primary completion date
- Dec 2027
- Lead sponsor
- University Hospital, Brest
- Diseases
- Stroke
- NCT number
- NCT06995040
What you commit to
- Study type: Interventional
- Planned participants: 1000
- From Jun 2025 to the primary completion date, Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Patients with transient neurological deficits resolving within one hour and normal brain imaging will be excluded.
- Not affiliated to social security
- Patient under legal protection or deprived of liberty by a judicial or administrative decision
- Patient unable to sign informed consent
- Patient whose follow-up will be impossible
Who the study is looking for
- Cases of stroke in the Brest Stroke Registry (BSR)
- Ability to sign informed consent
- Patients followed-up \> 4 years during the study period
- NIHSS score ≤ 5 on admission
- First stroke above 18 and before 75-year old
- Rankin before stroke \< 1
- Possibility to draw saliva samples for genomic study
- Possibility to perform Cerebral MRI
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU de Brest Coordinator of this site? Confirm its status | Brest | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.