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NCT06997809Recruiting

ENDometriosis: Evaluation of Detection and Need for ALGOlogic Care Before Surgery

Source: ClinicalTrials.gov · Last updated 4 Sept 2026

Brief summary (registry, in English)

Endometriosis surgery is required when medical treatment fails to release women from pain. However, complete surgery does not work every time to improve patients' symptoms. Algological care is one of the options to treat the pain before surgery and their related complications (neuropathy, sensitization, and catastrophism) that could be associated to nociceptive pain. But not all patients could benefit from this pathway and no screening strategy does exist to detect these complications that could be treated prior to endometriosis surgery

Status (registry)
Recruiting
Study type
Interventional
Enrollment
187 (estimated)
First submitted
5 Feb 2025
Start date
5 Aug 2026
Primary completion date
31 Dec 2030
Lead sponsor
University Hospital, Limoges
NCT number
NCT06997809

What you commit to

  • Study type: Interventional
  • Planned participants: 187
  • From 5 Aug 2026 to the primary completion date, 31 Dec 2030
  • 9 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Women undergoing surgery for the purpose of infertility
  • Patient with previous surgery for removal of deep lesions of endometriosis or endometriotic cysts (history of exploratory laparoscopy accepted)
  • Patient with a desire for pregnancy immediately and/or within one year after surgery
  • Patient who has already received algological treatment or who should receive it before surgery
  • Patient with previous other psychiatric disorders (depressive symptoms treated)

Other

  • Patient with suspicious lesions on MRI or specialized ultrasound.
  • A patient who needs to be treated for another uterine pathology at the same time.
  • Pregnant women
  • Women who refuse clinical examination (some algological tests couldn't be performed without clinical examination)
  • Women without rights

Who the study is looking for

  • Maternal age from 18 up to 50 years old (50 non included).
  • Women affiliated to social coverage insurance
  • Women who understand French
  • Women who signed the written consent
  • Women with impaired quality of life (pain) linked to endometriosis
  • Women with formal radiological signs of endometriosis (MRI lesions more than 5 mm or endometrioma more than 20 mm on radiological examinations).
  • Surgical indication for resection of lesions by laparoscopy or robotic surgery for management of pain or impairment of quality of life
  • Patients requiring complete conservative or radical resections of all lesions
  • Indication of surgery validated within dedicated meeting for endometriosis.
  • Purpose of pain associated or not with infertility
  • Date of surgery fixed with sufficient time for algological treatment. Maximum delay of 4 months between randomization and surgery

Age in the registry: 18 years to 50 years · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (9)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Bordeaux University Hospital
Coordinator of this site? Confirm its status
BordeauxFranceNot yet recruiting
IFEMENDO
Coordinator of this site? Confirm its status
BordeauxFranceNot yet recruiting
Versailles Hospital
Coordinator of this site? Confirm its status
Le ChesnayFranceNot yet recruiting
Saint Vincent de Paul Hospital
Coordinator of this site? Confirm its status
LilleFranceNot yet recruiting
Limoges university hospital
Coordinator of this site? Confirm its status
LimogesFranceRecruiting
Poissy-St-Germain Intercommunal hospital center
Coordinator of this site? Confirm its status
PoissyFranceNot yet recruiting
Poitiers University Hospital
Coordinator of this site? Confirm its status
PoitiersFranceNot yet recruiting
South Hospital Rennes University Hospital
Coordinator of this site? Confirm its status
RennesFranceNot yet recruiting
Mutual Clinic La Sagesse
Coordinator of this site? Confirm its status
RennesFranceNot yet recruiting

This page is information, not medical advice. Discuss any trial with your doctor.