NCT06997952CompletedPhase 1
Febuxostat Effect on Chronic Kidney Disease Progression And Carotid Intima-Media Thickness
Impact of Febuxostat on Disease Progression and Carotid Intima-Media Thickness in Patients With Chronic Kidney Disease
Source: ClinicalTrials.gov · Last updated 29 Jul 2026
Brief summary (registry, in English)
This study aimed to evaluate the impact of febuxostat on both carotid intima-media thickness and disease progression in individuals with chronic kidney disease
- Status (registry)
- Completed
- Phase (registry)
- Phase 1
- Study type
- Interventional
- Enrollment
- 50 (actual)
- First submitted
- 22 May 2025
- Start date
- May 2024
- Primary completion date
- Aug 2024
- Lead sponsor
- Ain Shams University
- Diseases
- Chronic kidney disease
- NCT number
- NCT06997952
What you commit to
- Study type: Interventional · Phase 1
- Participants enrolled: 50
- From May 2024 to the primary completion date, Aug 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients receiving mercaptopurine, theophylline and azathioprine.
- Patients on steroids or other immunosuppressive treatment.
Other illness
- Comprised active infections.
- Active and advanced malignancy.
- History of hypersensitivity to febuxostat.
- Patients with established cardiovascular disease.
- Patients with liver disease.
Other
- Acute kidney injury.
- Women who are taking oral contraceptives, pregnant or lactating
Who the study is looking for
- Age of 18 years or older
- CKD stages III to IV
- Asymptomatic hyper uricemia
- Stable dose of all medications including ACEIs or ARBs for blood pressure control at least three months before enrolling
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ain Shams University Coordinator of this site? Confirm its status | Cairo | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.