NCT06998940RecruitingPhase 3
Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations
Randomized Phase III Study of Second-Line Chemotherapy With or Without Panitumumab for KRAS Wild Type, Locally Advanced or Metastatic Pancreatic Adenocarcinoma
Source: ClinicalTrials.gov · Last updated 22 May 2026
Brief summary (registry, in English)
This phase III trial compares the effect of adding panitumumab to standard chemotherapy (with nanoliposomal Irinotecan, leucovorin, and 5-fluorouracil \[5-FU\] or irinotecan, leucovorin, and 5-FU or nab-paclitaxel and gemcitabine) versus standard chemotherapy alone in treating patients with KRAS wild type (WT) pancreatic ductal adenocarcinoma that cannot be removed by sugery (unresectable) or that has spread to nearby tissue or lymph nodes (locally advanced) or that has spread from where it first started (primary site) to other places in the body (metastatic). Panitumumab is a monoclonal antibody that may interfere with the ability of tumor cells to grow and spread. A monoclonal antibody is a type of protein that can bind to certain targets in the body, such as molecules that cause the body to make an immune response (antigens). Chemotherapy drugs, such as nanoliposomal irinotecan, leucovorin, 5-FU, irinotecan, nab-paclitaxel and gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Adding panitumumab to standard chemotherapy may be effective in treating patients with unresectable, locally advanced, or metastatic KRAS WT pancreatic ductal adenocarcinoma.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 94 (estimated)
- First submitted
- 21 May 2025
- Start date
- 13 May 2026
- Primary completion date
- 31 Dec 2029
- Lead sponsor
- SWOG Cancer Research Network
- Diseases
- Pancreatic cancer
- NCT number
- NCT06998940
What you commit to
- Study type: Interventional · Phase 3
- Planned participants: 94
- From 13 May 2026 to the primary completion date, 31 Dec 2029
- 274 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- Participants must have a histologically or cytologically confirmed diagnosis of ductal adenocarcinoma of the pancreas
- Participants must have previously documented KRAS wild type (i.e. absence of any KRAS mutation) and BRAF V600E wild type (i.e. absence of a BRAF V600E mutation) status determined by tumor tissue-based NGS assay. The testing must be done within a laboratory with Clinical Laboratory Improvement Act (CLIA), International Organization for Standardization (ISO)/International Electrotechnical Commission (IEC), College of American Pathologists (CAP), or similar certification status
- NOTE: Blood-based next generation sequencing (NGS) assays, such as circulating tumor deoxyribonucleic acid (DNA) (ctDNA) or liquid biopsies, will not be accepted for meeting eligibility criteria
- Participants must have documented unresectable and/or metastatic disease on CT or magnetic resonance imaging (MRI) imaging completed prior to randomization. Imaging must have been completed within 28 days prior to randomization for participants with measurable disease. CT scans or MRIs used to assess non-measurable disease must have been completed within 42 days prior to randomization. All disease must be assessed and documented on the Baseline Tumor Assessment Form (In calculating days of tests and measurements, the day a test or measurement is done is considered Day 0. Therefore, if a test is done on a Monday, the Monday 4 weeks later would be considered Day 28. This allows for efficient participant scheduling without exceeding the guidelines. If Day 14 or 28 falls on a weekend or holiday, the limit may be extended to the next working day)
- Participants must not have known mutations in PTEN, NRAS, EGFR extracellular domain exons 1-16, no amplifications of HER2 and MET, and no gene fusions of RET, NTRK1, and ALK by tumor tissue-based NGS analysis
- NOTE: Participants who are not tested for these mutations are eligible if they have previously documented KRAS wild type (i.e. absence of any KRAS mutation) and BRAF V600E wild type (i.e. absence of a BRAF V600E mutation) status
- Participants must not have known brain metastases or cranial epidural disease unless adequately treated with radiotherapy and/or surgery and stable for at least 28 days before randomization (In calculating days of tests and measurements, the day a test or measurement is done is considered Day 0. Therefore, if a test is done on a Monday, the Monday 4 weeks later would be considered Day 28. This allows for efficient participant scheduling without exceeding the guidelines. If Day 14 or 28 falls on a weekend or holiday, the limit may be extended to the next working day).
- NOTE: Participants must be neurologically asymptomatic and without corticosteroid treatment at the time of enrollment
- Participants must have received only one line of prior systemic cytotoxic chemotherapy for locally advanced or metastatic PDA, and have radiographically progressed, refractory, or intolerant to this therapy.
- Prior neoadjuvant or adjuvant therapy with 5-FU or gemcitabine-based chemotherapy counts as a line of therapy if the participant's disease progressed to locally advanced or metastatic disease within 6 months of completing treatment
- Participants with cancers harboring molecular alterations including microsatellite instability (MSI-high), elevated tumor mutational burden (TMB) (TMB ≥ 10 mut/Mb), and FGFR1-3, NRG1, and ROS fusions are allowed to have received an additional line of targeted therapy applicable to the respective molecular alterations at the treating investigators discretion.
- Prior maintenance therapy with Olaparib or Rucaparib for germline or somatic BRCA1/2 or PALB2 mutations does not count as a line of therapy.
- Participants must not have prior treatment with an anti-EGFR antibody (e.g., cetuximab or panitumumab)
- Participants must not have prior treatment with an EGFR tyrosine kinase inhibitor (e.g., erlotinib)
- Participants must not have received any pancreatic anticancer therapy (e.g., standard of care or investigational chemotherapy, molecularly targeted therapy, or radiation) within 14 days prior to randomization
- Participants must not have a known contraindication to receiving chosen chemotherapy backbone at the planned doses in accordance with the local approved label
- Participant must be ≥ 18 years old at the time of randomization
- Participants must have Zubrod performance status of 0-2
- Participants must have a complete medical history and physical exam within 28 days prior to randomization (In calculating days of tests and measurements, the day a test or measurement is done is considered Day 0. Therefore, if a test is done on a Monday, the Monday 4 weeks later would be considered Day 28. This allows for efficient participant scheduling without exceeding the guidelines. If Day 14 or 28 falls on a weekend or holiday, the limit may be extended to the next working day)
- Absolute neutrophil count ≥ 1.0 x 10\^3/uL (within 28 days prior to randomization) (In calculating days of tests and measurements, the day a test or measurement is done is considered Day 0. Therefore, if a test is done on a Monday, the Monday 4 weeks later would be considered Day 28. This allows for efficient participant scheduling without exceeding the guidelines. If Day 14 or 28 falls on a weekend or holiday, the limit may be extended to the next working day)
- Note: Use of growth factor support (e.g., Granulocyte Colony-Stimulating Factor \[G-CSF\] or romiplostim \[Nplate\]) is permitted, and prior use does not constitute an exclusion criterion. Recent blood transfusions are also allowed
- Hemoglobin ≥ 8 g/dL (within 28 days prior to randomization) (In calculating days of tests and measurements, the day a test or measurement is done is considered Day 0. Therefore, if a test is done on a Monday, the Monday 4 weeks later would be considered Day 28. This allows for efficient participant scheduling without exceeding the guidelines. If Day 14 or 28 falls on a weekend or holiday, the limit may be extended to the next working day)
- Note: Use of growth factor support (e.g., G-CSF or romiplostim \[Nplate\]) is permitted, and prior use does not constitute an exclusion criterion. Recent blood transfusions are also allowed
- Platelets ≥ 75 x 10\^3/uL (within 28 days prior to randomization) (In calculating days of tests and measurements, the day a test or measurement is done is considered Day 0. Therefore, if a test is done on a Monday, the Monday 4 weeks later would be considered Day 28. This allows for efficient participant scheduling without exceeding the guidelines. If Day 14 or 28 falls on a weekend or holiday, the limit may be extended to the next working day)
- Note: Use of growth factor support (e.g., G-CSF or romiplostim \[Nplate\]) is permitted, and prior use does not constitute an exclusion criterion. Recent blood transfusions are also allowed
- Total bilirubin ≤ 1.5 x institutional upper limit of normal (IULN) (within 28 days prior to randomization) (In calculating days of tests and measurements, the day a test or measurement is done is considered Day 0. Therefore, if a test is done on a Monday, the Monday 4 weeks later would be considered Day 28. This allows for efficient participant scheduling without exceeding the guidelines. If Day 14 or 28 falls on a weekend or holiday, the limit may be extended to the next working day)
- Aspartate aminotransferase (AST) ≤ 10 x upper limits of normal (ULN) (within 28 days prior to randomization) (In calculating days of tests and measurements, the day a test or measurement is done is considered Day 0. Therefore, if a test is done on a Monday, the Monday 4 weeks later would be considered Day 28. This allows for efficient participant scheduling without exceeding the guidelines. If Day 14 or 28 falls on a weekend or holiday, the limit may be extended to the next working day)
- Participants must have a creatinine ≤ the IULN OR measured OR calculated creatinine clearance ≥ 30 mL/min using the following Cockcroft-Gault Formula. This specimen must have been drawn and processed within 28 days prior to registration (In calculating days of tests and measurements, the day a test or measurement is done is considered Day 0. Therefore, if a test is done on a Monday, the Monday 4 weeks later would be considered Day 28. This allows for efficient participant scheduling without exceeding the guidelines. If Day 14 or 28 falls on a weekend or holiday, the limit may be extended to the next working day)
- Participants with known history of human immunodeficiency virus (HIV)-infection must be on effective anti-retroviral therapy at registration and have undetectable viral load test on the most recent test results obtained within 6 months prior to randomization
- Participants with a known history of chronic hepatitis B virus (HBV) infection must have undetectable HBV viral load while on suppressive therapy on the most recent test results obtained within 6 months prior to randomization, if indicated
- Participants with a known history of hepatitis C virus (HCV) infection must have been treated and cured. Participants currently being treated for HCV infection must have undetectable HCV viral load test on the most recent test results obtained within 6 months prior to randomization, if indicated
- Participants must not have a prior or concurrent malignancy whose natural history or treatment (in the opinion of the treating physician) has the potential to interfere with the safety or efficacy assessment of the investigational regimen
- Participants must not be pregnant or nursing (nursing includes breast milk fed to an infant by any means, including from the breast, milk expressed by hand, or pumped). Individuals who are of reproductive potential must have agreed to use an effective contraceptive method with details provided as a part of the consent process. A person who has had menses at any time in the preceding 12 consecutive months or who has semen likely to contain sperm is considered to be of "reproductive potential." In addition to routine contraceptive methods, "effective contraception" also includes refraining from sexual activity that might result in pregnancy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) including hysterectomy, bilateral oophorectomy, bilateral tubal ligation/occlusion, and vasectomy with testing showing no sperm in the semen
- Participants must be offered the opportunity to participate in specimen banking
- Participants who can complete patient reported outcomes (FACT-G and PRO-CTCAE) questionnaires in English or Spanish must be offered the opportunity to participate in the quality-of-life studies
- Participants must be informed of the investigational nature of this study and must sign and give informed consent in accordance with institutional and federal guidelines.
- For participants with impaired decision-making capabilities, legally authorized representatives may sign and give informed consent on behalf of study participants in accordance with applicable federal, local, and Central Institutional Review Board (CIRB) regulations
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (274)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Providence Regional Cancer System-Aberdeen Coordinator of this site? Confirm its status | Aberdeen | United States | Recruiting |
| Riverwood Healthcare Center Coordinator of this site? Confirm its status | Aitkin | United States | Recruiting |
| McFarland Clinic - Ames Coordinator of this site? Confirm its status | Ames | United States | Recruiting |
| Mary Greeley Medical Center Coordinator of this site? Confirm its status | Ames | United States | Recruiting |
| Community Hospital of Anaconda Coordinator of this site? Confirm its status | Anaconda | United States | Recruiting |
| Anchorage Associates in Radiation Medicine Coordinator of this site? Confirm its status | Anchorage | United States | Recruiting |
| Katmai Oncology Group Coordinator of this site? Confirm its status | Anchorage | United States | Recruiting |
| Alaska Breast Care and Surgery LLC Coordinator of this site? Confirm its status | Anchorage | United States | Recruiting |
| Alaska Women's Cancer Care Coordinator of this site? Confirm its status | Anchorage | United States | Recruiting |
| Alaska Oncology and Hematology LLC Coordinator of this site? Confirm its status | Anchorage | United States | Recruiting |
| Providence Alaska Medical Center Coordinator of this site? Confirm its status | Anchorage | United States | Recruiting |
| Mission Hope Medical Oncology - Arroyo Grande Coordinator of this site? Confirm its status | Arroyo Grande | United States | Recruiting |
| Northwest Wisconsin Cancer Center Coordinator of this site? Confirm its status | Ashland | United States | Recruiting |
| Duluth Clinic Ashland Coordinator of this site? Confirm its status | Ashland | United States | Recruiting |
| Emory University Hospital/Winship Cancer Institute Coordinator of this site? Confirm its status | Atlanta | United States | Recruiting |
| Emory Saint Joseph's Hospital Coordinator of this site? Confirm its status | Atlanta | United States | Recruiting |
| Emory University Hospital Midtown Coordinator of this site? Confirm its status | Atlanta | United States | Recruiting |
| Sutter Auburn Faith Hospital Coordinator of this site? Confirm its status | Auburn | United States | Recruiting |
| Sutter Cancer Centers Radiation Oncology Services-Auburn Coordinator of this site? Confirm its status | Auburn | United States | Recruiting |
| Sinai Hospital of Baltimore Coordinator of this site? Confirm its status | Baltimore | United States | Recruiting |
| Flaget Memorial Hospital Coordinator of this site? Confirm its status | Bardstown | United States | Recruiting |
| Our Lady of the Lake Physician Group Coordinator of this site? Confirm its status | Baton Rouge | United States | Recruiting |
| Our Lady of The Lake Coordinator of this site? Confirm its status | Baton Rouge | United States | Recruiting |
| LSU Health Baton Rouge-North Clinic Coordinator of this site? Confirm its status | Baton Rouge | United States | Recruiting |
| Bronson Battle Creek Coordinator of this site? Confirm its status | Battle Creek | United States | Recruiting |
| Essentia Health - Baxter Clinic Coordinator of this site? Confirm its status | Baxter | United States | Recruiting |
| PeaceHealth Saint Joseph Medical Center Coordinator of this site? Confirm its status | Bellingham | United States | Recruiting |
| Saint Charles Health System Coordinator of this site? Confirm its status | Bend | United States | Recruiting |
| Alta Bates Summit Medical Center-Herrick Campus Coordinator of this site? Confirm its status | Berkeley | United States | Recruiting |
| Billings Clinic Cancer Center Coordinator of this site? Confirm its status | Billings | United States | Recruiting |
| Illinois CancerCare-Bloomington Coordinator of this site? Confirm its status | Bloomington | United States | Recruiting |
| Saint Luke's Cancer Institute - Boise Coordinator of this site? Confirm its status | Boise | United States | Recruiting |
| McFarland Clinic - Boone Coordinator of this site? Confirm its status | Boone | United States | Suspended |
| Bozeman Health Deaconess Hospital Coordinator of this site? Confirm its status | Bozeman | United States | Recruiting |
| Essentia Health Saint Joseph's Medical Center Coordinator of this site? Confirm its status | Brainerd | United States | Recruiting |
| Providence Saint Joseph Medical Center/Disney Family Cancer Center Coordinator of this site? Confirm its status | Burbank | United States | Recruiting |
| Mills-Peninsula Medical Center Coordinator of this site? Confirm its status | Burlingame | United States | Recruiting |
| Sutter Cancer Centers Radiation Oncology Services-Cameron Park Coordinator of this site? Confirm its status | Cameron Park | United States | Recruiting |
| Illinois CancerCare-Canton Coordinator of this site? Confirm its status | Canton | United States | Recruiting |
| Saint Francis Medical Center Coordinator of this site? Confirm its status | Cape Girardeau | United States | Recruiting |
| Memorial Hospital of Carbondale Coordinator of this site? Confirm its status | Carbondale | United States | Recruiting |
| Mercy San Juan Medical Center Coordinator of this site? Confirm its status | Carmichael | United States | Recruiting |
| Mercy Cancer Center - Carmichael Coordinator of this site? Confirm its status | Carmichael | United States | Recruiting |
| SIH Cancer Institute Coordinator of this site? Confirm its status | Carterville | United States | Recruiting |
| Illinois CancerCare-Carthage Coordinator of this site? Confirm its status | Carthage | United States | Recruiting |
| Eden Hospital Medical Center Coordinator of this site? Confirm its status | Castro Valley | United States | Recruiting |
| Mercy Hospital Coordinator of this site? Confirm its status | Cedar Rapids | United States | Recruiting |
| Oncology Associates at Mercy Medical Center Coordinator of this site? Confirm its status | Cedar Rapids | United States | Recruiting |
| Miami Valley Hospital South Coordinator of this site? Confirm its status | Centerville | United States | Recruiting |
| Providence Regional Cancer System-Centralia Coordinator of this site? Confirm its status | Centralia | United States | Recruiting |
| Centralia Oncology Clinic Coordinator of this site? Confirm its status | Centralia | United States | Recruiting |
| Christiana Care Health System-Concord Health Center Coordinator of this site? Confirm its status | Chadds Ford | United States | Recruiting |
| Memorial Hospital of Laramie County Coordinator of this site? Confirm its status | Cheyenne | United States | Recruiting |
| Bethesda North Hospital Coordinator of this site? Confirm its status | Cincinnati | United States | Recruiting |
| TriHealth Cancer Institute-Westside Coordinator of this site? Confirm its status | Cincinnati | United States | Recruiting |
| University of Cincinnati Cancer Center-UC Medical Center Coordinator of this site? Confirm its status | Cincinnati | United States | Recruiting |
| TriHealth Cancer Institute-Anderson Coordinator of this site? Confirm its status | Cincinnati | United States | Recruiting |
| Good Samaritan Hospital - Cincinnati Coordinator of this site? Confirm its status | Cincinnati | United States | Recruiting |
| Clackamas Radiation Oncology Center Coordinator of this site? Confirm its status | Clackamas | United States | Recruiting |
| Southeastern Medical Oncology Center-Clinton Coordinator of this site? Confirm its status | Clinton | United States | Recruiting |
| Mercy Cancer Center-West Lakes Coordinator of this site? Confirm its status | Clive | United States | Recruiting |
| Billings Clinic-Cody Coordinator of this site? Confirm its status | Cody | United States | Recruiting |
| Kootenai Health - Coeur d'Alene Coordinator of this site? Confirm its status | Coeur d'Alene | United States | Recruiting |
| Baptist Memorial Hospital and Cancer Center-Collierville Coordinator of this site? Confirm its status | Collierville | United States | Recruiting |
| Penrose-Saint Francis Healthcare Coordinator of this site? Confirm its status | Colorado Springs | United States | Recruiting |
| Rocky Mountain Cancer Centers-Penrose Coordinator of this site? Confirm its status | Colorado Springs | United States | Recruiting |
| Saint Francis Cancer Center Coordinator of this site? Confirm its status | Colorado Springs | United States | Recruiting |
| Baptist Memorial Hospital and Cancer Center-Golden Triangle Coordinator of this site? Confirm its status | Columbus | United States | Recruiting |
| Bay Area Hospital Coordinator of this site? Confirm its status | Coos Bay | United States | Recruiting |
| Commonwealth Cancer Center-Corbin Coordinator of this site? Confirm its status | Corbin | United States | Recruiting |
| Greater Regional Medical Center Coordinator of this site? Confirm its status | Creston | United States | Recruiting |
| Essentia Health - Saint Joseph's Crosslake Clinic Coordinator of this site? Confirm its status | Crosslake | United States | Recruiting |
| Carle at The Riverfront Coordinator of this site? Confirm its status | Danville | United States | Recruiting |
| Sutter Davis Hospital Coordinator of this site? Confirm its status | Davis | United States | Recruiting |
| Miami Valley Hospital North Coordinator of this site? Confirm its status | Dayton | United States | Recruiting |
| Miami Valley Hospital Coordinator of this site? Confirm its status | Dayton | United States | Recruiting |
| Premier Blood and Cancer Center Coordinator of this site? Confirm its status | Dayton | United States | Recruiting |
| Emory Decatur Hospital Coordinator of this site? Confirm its status | Decatur | United States | Recruiting |
| Cancer Care Specialists of Illinois - Decatur Coordinator of this site? Confirm its status | Decatur | United States | Recruiting |
| Decatur Memorial Hospital Coordinator of this site? Confirm its status | Decatur | United States | Recruiting |
| Essentia Health - Deer River Clinic Coordinator of this site? Confirm its status | Deer River | United States | Recruiting |
| Mercy Medical Center - Des Moines Coordinator of this site? Confirm its status | Des Moines | United States | Recruiting |
| Essentia Health Saint Mary's - Detroit Lakes Clinic Coordinator of this site? Confirm its status | Detroit Lakes | United States | Recruiting |
| Illinois CancerCare-Dixon Coordinator of this site? Confirm its status | Dixon | United States | Recruiting |
| Essentia Health Saint Mary's Medical Center Coordinator of this site? Confirm its status | Duluth | United States | Recruiting |
| Essentia Health Cancer Center Coordinator of this site? Confirm its status | Duluth | United States | Recruiting |
| Miller-Dwan Hospital Coordinator of this site? Confirm its status | Duluth | United States | Recruiting |
| Mercy Medical Center Coordinator of this site? Confirm its status | Durango | United States | Recruiting |
| CommonSpirit Cancer Center Mercy Coordinator of this site? Confirm its status | Durango | United States | Recruiting |
| Swedish Cancer Institute-Edmonds Coordinator of this site? Confirm its status | Edmonds | United States | Recruiting |
| Crossroads Cancer Center Coordinator of this site? Confirm its status | Effingham | United States | Recruiting |
| Carle Physician Group-Effingham Coordinator of this site? Confirm its status | Effingham | United States | Recruiting |
| Mercy Cancer Center - Elk Grove Coordinator of this site? Confirm its status | Elk Grove | United States | Recruiting |
| Christiana Care - Union Hospital Coordinator of this site? Confirm its status | Elkton | United States | Recruiting |
| Essentia Health - Ely Clinic Coordinator of this site? Confirm its status | Ely | United States | Recruiting |
| OSF Saint Francis Hospital and Medical Group Coordinator of this site? Confirm its status | Escanaba | United States | Recruiting |
| Illinois CancerCare-Eureka Coordinator of this site? Confirm its status | Eureka | United States | Recruiting |
| Providence Regional Cancer Partnership Coordinator of this site? Confirm its status | Everett | United States | Recruiting |
| Inova Fair Oaks Hospital Coordinator of this site? Confirm its status | Fairfax | United States | Recruiting |
| Inova Schar Cancer Institute Coordinator of this site? Confirm its status | Fairfax | United States | Recruiting |
| Essentia Health Cancer Center-South University Clinic Coordinator of this site? Confirm its status | Fargo | United States | Recruiting |
| Parkland Health Center - Farmington Coordinator of this site? Confirm its status | Farmington | United States | Recruiting |
| Highlands Oncology Group - Fayetteville Coordinator of this site? Confirm its status | Fayetteville | United States | Recruiting |
| McFarland Clinic - Trinity Cancer Center Coordinator of this site? Confirm its status | Fort Dodge | United States | Recruiting |
| Essentia Health - Fosston Coordinator of this site? Confirm its status | Fosston | United States | Recruiting |
| Atrium Medical Center-Middletown Regional Hospital Coordinator of this site? Confirm its status | Franklin | United States | Recruiting |
| Palo Alto Medical Foundation-Fremont Coordinator of this site? Confirm its status | Fremont | United States | Recruiting |
| Saint Luke's Cancer Institute - Fruitland Coordinator of this site? Confirm its status | Fruitland | United States | Recruiting |
| Illinois CancerCare-Galesburg Coordinator of this site? Confirm its status | Galesburg | United States | Recruiting |
| Southeastern Medical Oncology Center-Goldsboro Coordinator of this site? Confirm its status | Goldsboro | United States | Recruiting |
| CHI Health Saint Francis Coordinator of this site? Confirm its status | Grand Island | United States | Recruiting |
| Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital Coordinator of this site? Confirm its status | Grand Rapids | United States | Recruiting |
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital Coordinator of this site? Confirm its status | Grand Rapids | United States | Recruiting |
| Trinity Health Grand Rapids Hospital Coordinator of this site? Confirm its status | Grand Rapids | United States | Recruiting |
| Great Falls Clinic Coordinator of this site? Confirm its status | Great Falls | United States | Recruiting |
| Benefis Sletten Cancer Institute Coordinator of this site? Confirm its status | Great Falls | United States | Recruiting |
| Saint Vincent Hospital Cancer Center Green Bay Coordinator of this site? Confirm its status | Green Bay | United States | Recruiting |
| Saint Vincent Hospital Cancer Center at Saint Mary's Coordinator of this site? Confirm its status | Green Bay | United States | Recruiting |
| Miami Valley Cancer Care and Infusion Coordinator of this site? Confirm its status | Greenville | United States | Recruiting |
| Baptist Cancer Center-Grenada Coordinator of this site? Confirm its status | Grenada | United States | Recruiting |
| Hi-Line Sletten Cancer Center Coordinator of this site? Confirm its status | Havre | United States | Recruiting |
| Tamarack Health Hayward Medical Center Coordinator of this site? Confirm its status | Hayward | United States | Recruiting |
| Essentia Health-Hayward Clinic Coordinator of this site? Confirm its status | Hayward | United States | Recruiting |
| Benefis Helena Specialty Center Coordinator of this site? Confirm its status | Helena | United States | Recruiting |
| Essentia Health Hibbing Clinic Coordinator of this site? Confirm its status | Hibbing | United States | Recruiting |
| Providence Hood River Memorial Hospital Coordinator of this site? Confirm its status | Hood River | United States | Recruiting |
| Essentia Health - International Falls Clinic Coordinator of this site? Confirm its status | International Falls | United States | Recruiting |
| Swedish Cancer Institute-Issaquah Coordinator of this site? Confirm its status | Issaquah | United States | Recruiting |
| Southeastern Medical Oncology Center-Jacksonville Coordinator of this site? Confirm its status | Jacksonville | United States | Recruiting |
| Essentia Health - Jamestown Clinic Coordinator of this site? Confirm its status | Jamestown | United States | Recruiting |
| McFarland Clinic - Jefferson Coordinator of this site? Confirm its status | Jefferson | United States | Suspended |
| Emory Johns Creek Hospital Coordinator of this site? Confirm its status | Johns Creek | United States | Recruiting |
| NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro Coordinator of this site? Confirm its status | Jonesboro | United States | Recruiting |
| Beacon Kalamazoo Coordinator of this site? Confirm its status | Kalamazoo | United States | Recruiting |
| West Michigan Cancer Center Coordinator of this site? Confirm its status | Kalamazoo | United States | Recruiting |
| Beacon Kalamazoo Cancer Center Coordinator of this site? Confirm its status | Kalamazoo | United States | Recruiting |
| Bronson Methodist Hospital Coordinator of this site? Confirm its status | Kalamazoo | United States | Recruiting |
| Logan Health Medical Center Coordinator of this site? Confirm its status | Kalispell | United States | Recruiting |
| CHI Health Good Samaritan Coordinator of this site? Confirm its status | Kearney | United States | Recruiting |
| Kadlec Clinic Hematology and Oncology Coordinator of this site? Confirm its status | Kennewick | United States | Recruiting |
| Illinois CancerCare-Kewanee Clinic Coordinator of this site? Confirm its status | Kewanee | United States | Recruiting |
| Providence Regional Cancer System-Lacey Coordinator of this site? Confirm its status | Lacey | United States | Recruiting |
| Gundersen Lutheran Medical Center Coordinator of this site? Confirm its status | La Crosse | United States | Recruiting |
| The Watson Clinic Coordinator of this site? Confirm its status | Lakeland | United States | Recruiting |
| Saint Anthony Hospital Coordinator of this site? Confirm its status | Lakewood | United States | Recruiting |
| Beebe Medical Center Coordinator of this site? Confirm its status | Lewes | United States | Recruiting |
| Saint Joseph Radiation Oncology Resource Center Coordinator of this site? Confirm its status | Lexington | United States | Recruiting |
| Saint Joseph Hospital East Coordinator of this site? Confirm its status | Lexington | United States | Recruiting |
| Saint Joseph Hospital Coordinator of this site? Confirm its status | Lexington | United States | Recruiting |
| Saint Joseph London Coordinator of this site? Confirm its status | London | United States | Recruiting |
| Longmont United Hospital Coordinator of this site? Confirm its status | Longmont | United States | Recruiting |
| PeaceHealth Saint John Medical Center Coordinator of this site? Confirm its status | Longview | United States | Recruiting |
| Illinois CancerCare-Macomb Coordinator of this site? Confirm its status | Macomb | United States | Recruiting |
| McFarland Clinic - Marshalltown Coordinator of this site? Confirm its status | Marshalltown | United States | Recruiting |
| Carle Physician Group-Mattoon/Charleston Coordinator of this site? Confirm its status | Mattoon | United States | Recruiting |
| Baptist Memorial Hospital and Cancer Center-Memphis Coordinator of this site? Confirm its status | Memphis | United States | Recruiting |
| Mercy Cancer Center Coordinator of this site? Confirm its status | Merced | United States | Recruiting |
| Saint Luke's Cancer Institute - Meridian Coordinator of this site? Confirm its status | Meridian | United States | Recruiting |
| Beebe South Coastal Health Campus Coordinator of this site? Confirm its status | Millville | United States | Recruiting |
| Saint Patrick Hospital - Community Hospital Coordinator of this site? Confirm its status | Missoula | United States | Recruiting |
| Community Medical Center Coordinator of this site? Confirm its status | Missoula | United States | Recruiting |
| Memorial Medical Center Coordinator of this site? Confirm its status | Modesto | United States | Recruiting |
| Essentia Health - Moose Lake Clinic Coordinator of this site? Confirm its status | Moose Lake | United States | Recruiting |
| Palo Alto Medical Foundation-Gynecologic Oncology Coordinator of this site? Confirm its status | Mountain View | United States | Recruiting |
| Palo Alto Medical Foundation-Camino Division Coordinator of this site? Confirm its status | Mountain View | United States | Recruiting |
| Saint Joseph Mount Sterling Coordinator of this site? Confirm its status | Mount Sterling | United States | Recruiting |
| Skagit Regional Health Cancer Care Center Coordinator of this site? Confirm its status | Mount Vernon | United States | Recruiting |
| Trinity Health Muskegon Hospital Coordinator of this site? Confirm its status | Muskegon | United States | Recruiting |
| Saint Luke's Cancer Institute - Nampa Coordinator of this site? Confirm its status | Nampa | United States | Recruiting |
| Providence Queen of The Valley Coordinator of this site? Confirm its status | Napa | United States | Recruiting |
| Baptist Memorial Hospital and Cancer Center-Union County Coordinator of this site? Confirm its status | New Albany | United States | Recruiting |
| Christiana Care Health System-Christiana Hospital Coordinator of this site? Confirm its status | Newark | United States | Recruiting |
| Helen F Graham Cancer Center Coordinator of this site? Confirm its status | Newark | United States | Recruiting |
| Medical Oncology Hematology Consultants PA Coordinator of this site? Confirm its status | Newark | United States | Recruiting |
| Providence Newberg Medical Center Coordinator of this site? Confirm its status | Newberg | United States | Recruiting |
| Corewell Health Lakeland Hospitals - Niles Hospital Coordinator of this site? Confirm its status | Niles | United States | Recruiting |
| Carle Cancer Institute Normal Coordinator of this site? Confirm its status | Normal | United States | Recruiting |
| Carle BroMenn Medical Center Coordinator of this site? Confirm its status | Normal | United States | Recruiting |
| Cancer and Hematology Centers of Western Michigan - Norton Shores Coordinator of this site? Confirm its status | Norton Shores | United States | Recruiting |
| Sutter Cancer Research Consortium Coordinator of this site? Confirm its status | Novato | United States | Recruiting |
| Saint Vincent Hospital Cancer Center at Oconto Falls Coordinator of this site? Confirm its status | Oconto Falls | United States | Recruiting |
| HSHS Saint Elizabeth's Hospital Coordinator of this site? Confirm its status | O'Fallon | United States | Recruiting |
| Cancer Care Center of O'Fallon Coordinator of this site? Confirm its status | O'Fallon | United States | Recruiting |
| Alegent Health Bergan Mercy Medical Center Coordinator of this site? Confirm its status | Omaha | United States | Recruiting |
| Creighton University Medical Center Coordinator of this site? Confirm its status | Omaha | United States | Recruiting |
| Alegent Health Immanuel Medical Center Coordinator of this site? Confirm its status | Omaha | United States | Recruiting |
| Alegent Health Lakeside Hospital Coordinator of this site? Confirm its status | Omaha | United States | Recruiting |
| Providence Willamette Falls Medical Center Coordinator of this site? Confirm its status | Oregon City | United States | Recruiting |
| Illinois CancerCare-Ottawa Clinic Coordinator of this site? Confirm its status | Ottawa | United States | Recruiting |
| Baptist Memorial Hospital and Cancer Center-Oxford Coordinator of this site? Confirm its status | Oxford | United States | Recruiting |
| Palo Alto Medical Foundation Health Care Coordinator of this site? Confirm its status | Palo Alto | United States | Recruiting |
| Essentia Health - Park Rapids Coordinator of this site? Confirm its status | Park Rapids | United States | Recruiting |
| Illinois CancerCare-Pekin Coordinator of this site? Confirm its status | Pekin | United States | Recruiting |
| Illinois CancerCare-Peoria Coordinator of this site? Confirm its status | Peoria | United States | Recruiting |
| Essentia Health - Saint Joseph's Pequot Lakes Clinic Coordinator of this site? Confirm its status | Pequot Lakes | United States | Recruiting |
| Illinois CancerCare-Peru Coordinator of this site? Confirm its status | Peru | United States | Recruiting |
| Valley Radiation Oncology Coordinator of this site? Confirm its status | Peru | United States | Recruiting |
| Cancer Center at Saint Joseph's Coordinator of this site? Confirm its status | Phoenix | United States | Recruiting |
| FirstHealth of the Carolinas-Moore Regional Hospital Coordinator of this site? Confirm its status | Pinehurst | United States | Recruiting |
| Essentia Health - Saint Joseph's Pine River Clinic Coordinator of this site? Confirm its status | Pine River | United States | Recruiting |
| Providence Saint Vincent Medical Center Coordinator of this site? Confirm its status | Portland | United States | Recruiting |
| Providence Portland Medical Center Coordinator of this site? Confirm its status | Portland | United States | Recruiting |
| Kootenai Clinic Cancer Services - Post Falls Coordinator of this site? Confirm its status | Post Falls | United States | Recruiting |
| Illinois CancerCare-Princeton Coordinator of this site? Confirm its status | Princeton | United States | Recruiting |
| Saint Mary Corwin Medical Center Coordinator of this site? Confirm its status | Pueblo | United States | Recruiting |
| Northwest Hospital Center Coordinator of this site? Confirm its status | Randallstown | United States | Recruiting |
| Rapid City Regional Hospital Coordinator of this site? Confirm its status | Rapid City | United States | Recruiting |
| Saint Charles Health System-Redmond Coordinator of this site? Confirm its status | Redmond | United States | Recruiting |
| Corewell Health Reed City Hospital Coordinator of this site? Confirm its status | Reed City | United States | Recruiting |
| Beebe Health Campus Coordinator of this site? Confirm its status | Rehoboth Beach | United States | Recruiting |
| Mercy Cancer Center - Rocklin Coordinator of this site? Confirm its status | Rocklin | United States | Recruiting |
| Highlands Oncology Group - Rogers Coordinator of this site? Confirm its status | Rogers | United States | Recruiting |
| Sutter Cancer Centers Radiation Oncology Services-Roseville Coordinator of this site? Confirm its status | Roseville | United States | Recruiting |
| Sutter Roseville Medical Center Coordinator of this site? Confirm its status | Roseville | United States | Recruiting |
| Mercy Cancer Center - Sacramento Coordinator of this site? Confirm its status | Sacramento | United States | Recruiting |
| Sutter Medical Center Sacramento Coordinator of this site? Confirm its status | Sacramento | United States | Recruiting |
| Sainte Genevieve County Memorial Hospital Coordinator of this site? Confirm its status | Sainte Genevieve | United States | Recruiting |
| Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center Coordinator of this site? Confirm its status | Saint Joseph | United States | Recruiting |
| Corewell Health Lakeland Hospitals - Saint Joseph Hospital Coordinator of this site? Confirm its status | Saint Joseph | United States | Recruiting |
| Kootenai Clinic Cancer Services - Sandpoint Coordinator of this site? Confirm its status | Sandpoint | United States | Recruiting |
| Essentia Health Sandstone Coordinator of this site? Confirm its status | Sandstone | United States | Recruiting |
| California Pacific Medical Center-Pacific Campus Coordinator of this site? Confirm its status | San Francisco | United States | Recruiting |
| Pacific Central Coast Health Center-San Luis Obispo Coordinator of this site? Confirm its status | San Luis Obispo | United States | Recruiting |
| Mills Health Center Coordinator of this site? Confirm its status | San Mateo | United States | Recruiting |
| Ridley-Tree Cancer Center Coordinator of this site? Confirm its status | Santa Barbara | United States | Recruiting |
| Santa Cruz Radiation Oncology Medical Group Coordinator of this site? Confirm its status | Santa Cruz | United States | Recruiting |
| Palo Alto Medical Foundation-Santa Cruz Coordinator of this site? Confirm its status | Santa Cruz | United States | Recruiting |
| Mission Hope Medical Oncology - Santa Maria Coordinator of this site? Confirm its status | Santa Maria | United States | Recruiting |
| Providence Santa Rosa Memorial Hospital Coordinator of this site? Confirm its status | Santa Rosa | United States | Recruiting |
| Providence Medical Foundation - Santa Rosa Coordinator of this site? Confirm its status | Santa Rosa | United States | Recruiting |
| Sutter Pacific Medical Foundation Coordinator of this site? Confirm its status | Santa Rosa | United States | Recruiting |
| University of Washington Medical Center - Montlake Coordinator of this site? Confirm its status | Seattle | United States | Recruiting |
| Swedish Medical Center-First Hill Coordinator of this site? Confirm its status | Seattle | United States | Recruiting |
| Swedish Medical Center-Ballard Campus Coordinator of this site? Confirm its status | Seattle | United States | Recruiting |
| Swedish Medical Center-Cherry Hill Coordinator of this site? Confirm its status | Seattle | United States | Recruiting |
| Fred Hutchinson Cancer Center Coordinator of this site? Confirm its status | Seattle | United States | Recruiting |
| PeaceHealth United General Medical Center Coordinator of this site? Confirm its status | Sedro-Woolley | United States | Recruiting |
| Sheboygan Physicians Group Coordinator of this site? Confirm its status | Sheboygan | United States | Recruiting |
| Saint Vincent Hospital Cancer Center at Sheboygan Coordinator of this site? Confirm its status | Sheboygan | United States | Recruiting |
| Saint Michael Cancer Center Coordinator of this site? Confirm its status | Silverdale | United States | Recruiting |
| Baptist Memorial Hospital and Cancer Center-Desoto Coordinator of this site? Confirm its status | Southhaven | United States | Recruiting |
| Cancer Care Northwest-Valley Coordinator of this site? Confirm its status | Spokane | United States | Recruiting |
| Cancer Care Northwest - Spokane South Coordinator of this site? Confirm its status | Spokane | United States | Recruiting |
| Cancer Care Northwest-North Spokane Coordinator of this site? Confirm its status | Spokane | United States | Recruiting |
| Essentia Health-Spooner Clinic Coordinator of this site? Confirm its status | Spooner | United States | Recruiting |
| Highlands Oncology Group Coordinator of this site? Confirm its status | Springdale | United States | Recruiting |
| Southern Illinois University School of Medicine Coordinator of this site? Confirm its status | Springfield | United States | Recruiting |
| Springfield Clinic Coordinator of this site? Confirm its status | Springfield | United States | Recruiting |
| Springfield Memorial Hospital Coordinator of this site? Confirm its status | Springfield | United States | Recruiting |
| Stamford Hospital/Bennett Cancer Center Coordinator of this site? Confirm its status | Stamford | United States | Recruiting |
| Essentia Health - Saint Joseph's Staples Clinic Coordinator of this site? Confirm its status | Staples | United States | Recruiting |
| Missouri Baptist Medical Center Coordinator of this site? Confirm its status | St Louis | United States | Recruiting |
| Saint Joseph's Medical Center Coordinator of this site? Confirm its status | Stockton | United States | Recruiting |
| Saint Vincent Hospital Cancer Center at Sturgeon Bay Coordinator of this site? Confirm its status | Sturgeon Bay | United States | Recruiting |
| Missouri Baptist Sullivan Hospital Coordinator of this site? Confirm its status | Sullivan | United States | Recruiting |
| Palo Alto Medical Foundation-Sunnyvale Coordinator of this site? Confirm its status | Sunnyvale | United States | Recruiting |
| BJC Outpatient Center at Sunset Hills Coordinator of this site? Confirm its status | Sunset Hills | United States | Recruiting |
| Essentia Health Saint Mary's Hospital - Superior Coordinator of this site? Confirm its status | Superior | United States | Recruiting |
| Munson Medical Center Coordinator of this site? Confirm its status | Traverse City | United States | Recruiting |
| Upper Valley Medical Center Coordinator of this site? Confirm its status | Troy | United States | Recruiting |
| Saint Luke's Cancer Institute - Twin Falls Coordinator of this site? Confirm its status | Twin Falls | United States | Recruiting |
| Carle Cancer Center Coordinator of this site? Confirm its status | Urbana | United States | Recruiting |
| Sutter Solano Medical Center/Cancer Center Coordinator of this site? Confirm its status | Vallejo | United States | Recruiting |
| PeaceHealth Southwest Medical Center Coordinator of this site? Confirm its status | Vancouver | United States | Recruiting |
| Essentia Health Virginia Clinic Coordinator of this site? Confirm its status | Virginia | United States | Recruiting |
| Providence Saint Mary Regional Cancer Center Coordinator of this site? Confirm its status | Walla Walla | United States | Recruiting |
| Illinois CancerCare - Washington Coordinator of this site? Confirm its status | Washington | United States | Recruiting |
| University of Cincinnati Cancer Center-West Chester Coordinator of this site? Confirm its status | West Chester | United States | Recruiting |
| Mercy Medical Center-West Lakes Coordinator of this site? Confirm its status | West Des Moines | United States | Recruiting |
| William E Kahlert Regional Cancer Center/Sinai Hospital Coordinator of this site? Confirm its status | Westminster | United States | Recruiting |
| Saint Anthony North Hospital Coordinator of this site? Confirm its status | Westminster | United States | Recruiting |
| Christiana Care Health System-Wilmington Hospital Coordinator of this site? Confirm its status | Wilmington | United States | Recruiting |
| Woodland Memorial Hospital Coordinator of this site? Confirm its status | Woodland | United States | Recruiting |
| University of Michigan Health - West Coordinator of this site? Confirm its status | Wyoming | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.