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NCT06999213Not yet recruitingEarly phase 1

Lower Limb ExoNET: Development and Evaluation for Gait Assistance With Stroke Survivors

Source: ClinicalTrials.gov · Last updated 30 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

Stroke-related gait impairments, such as poor limb coordination, imbalance, and reduced push-off strength, are often addressed using robotic systems or electrical stimulation, which can be costly, invasive, or insufficient for long-term recovery. Current devices often assist movement but fail to promote functional motor learning. Research supports rehabilitation strategies that amplify gait errors to drive neuroplasticity and adaptation. The LegExoNET (Exoskeletal Network for Elastic Torque) is a novel, passive wearable exoskeleton designed to address this need by enabling both assistive and therapeutic gait training. It stores and releases elastic energy to aid movement while allowing natural joint motion. The system aims to support individuals post-stroke transitioning to independent rehabilitation by offering a lightweight, affordable, and adaptive solution. Initial testing will focus on healthy individuals to assess safety and feasibility before expanding to stroke populations. The LegExoNET has the potential to enhance gait recovery and reduce therapist burden through error augmentation and personalized support, both in clinical and at-home settings.

Status (registry)
Not yet recruiting
Phase (registry)
Early phase 1
Study type
Interventional
Enrollment
20 (estimated)
First submitted
7 Apr 2025
Start date
31 Jan 2026
Primary completion date
31 Dec 2029
Lead sponsor
Shirley Ryan AbilityLab
Diseases
Stroke
NCT number
NCT06999213

What you commit to

  • Study type: Interventional · Early phase 1
  • Planned participants: 20
  • From 31 Jan 2026 to the primary completion date, 31 Dec 2029
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • History of stroke, SCI, or other neurological medical diagnoses
  • Skin allergies or irritation; open wounds

Other

  • Pregnant
  • Severe medical diagnoses (e.g. cardiovascular, orthopedic)
  • Prisoners
  • Cognitively impaired adults

Who the study is looking for

  • Age 18-70 years old
  • Ability to provide informed consent
  • Capable of ambulating without the use of assistive devices for 2 hours

Age in the registry: 18 years to 70 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.