NCT06999434RecruitingPhase 1
Exploring the Utility of [18F]3F4AP for Demyelination Imaging
Source: ClinicalTrials.gov · Last updated 9 Sept 2026
Brief summary (registry, in English)
The overall objective is to obtain an assessment of the pharmacokinetics of \[18F\]3F4AP in healthy volunteers and subjects with demyelinating diseases such as mild cognitive impairment (MCI), Alzheimer's Disease (AD), Multiple Sclerosis (MS), Spinal Cord Injury (SCI) and Spinal radiculopathy (SR).
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 1
- Study type
- Interventional
- Enrollment
- 105 (estimated)
- First submitted
- 15 May 2025
- Start date
- 5 May 2025
- Primary completion date
- 5 May 2030
- Lead sponsor
- Yale University
- Diseases
- Alzheimer disease, Multiple sclerosis
- NCT number
- NCT06999434
What you commit to
- Study type: Interventional · Phase 1
- Planned participants: 105
- From 5 May 2025 to the primary completion date, 5 May 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- Inclusion:
- Male and Female subjects must be ≥18 and \<90 years of age;
- Able to understand and provide informed consent prior to study procedures
- Must be in good health
- Exclusion:
- Less than 18 years of age;
- Pregnant or breastfeeding;
- Any significant systemic illness or unstable medical condition;
- Pre-existing medical conditions or claustrophobic reactions;
- Research-related radiation exposure exceeds current PET Center guidelines (i.e. 50 mSv in the prior 12 months);
- History of a bleeding disorder or are currently taking anticoagulants.
Age in the registry: 18 years to 90 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Yale University PET Center Coordinator of this site? Confirm its status | New Haven | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.