NCT07001631Recruiting
Effect of EMDR for Reduction of Pain Interference in Children With Sickle Cell Disease
Source: ClinicalTrials.gov · Last updated 3 Jun 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Children with sickle cell disease may experience frequent painful episodes. This, together with the traumatic experiences during a hospitalization, can lead to the development of posttraumatic stress reactions. As the stress can trigger painful episodes (pain crisis) in children with sickle cell disease, the investigators think that treating these stress symptoms can reduce the pain-related problems in their lives. Eye Movement Desensitization and Reprocessing (EMDR) is proven to be an effective trauma treatment for posttraumatic stress disorder. Research studies show that EMDR can reduce pain in adults. The investigators want to study now if EMDR effective is in reducing pain-related problems in children with sickle cell disease.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 28 Apr 2025
- Start date
- 20 Sept 2024
- Primary completion date
- 1 Jul 2026
- Lead sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
- Diseases
- Sickle cell disease
- NCT number
- NCT07001631
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 20 Sept 2024 to the primary completion date, 1 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Undergone successful stem cell transplantation
- Current unsafety that is likely to interfere with psychological therapy for example ongoing domestic violence
- Receiving psychological (trauma) treatment by another therapist at the same time
Other illness
- Major interfering acute medical or psychiatric condition, such as psychosis, substance dependence, current severe self-harm or high risk for suicide requiring immediate treatment
Other
- Pregnant adolescents
- IQ estimated to be \< 80 based on information contained in the medical history or information from educational services/school
Who the study is looking for
- Medical diagnosis of SCD
- Age between 6 and 18 years old
- Elevated pain interference scores: Reporting above the clinical cut-off T-score of 49 on PROMIS Pain Interference (parent-proxy version for children from 6-7 years and self-report version for children from 8 years).
- Having sufficient knowledge of the Dutch or English languages to complete the assessments
Age in the registry: 6 years to 18 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Amsterdam UMC Coordinator of this site? Confirm its status | Amsterdam | Netherlands | Recruiting |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.