NCT07002554Enrolling by invitationPhase 2
Bright Light Therapy for Depressed Geriatric Inpatients
The LIGHT-60 Trial - Light Intervention for Geriatric Patients Hospitalized for Depression Treatment
Source: ClinicalTrials.gov · Last updated 16 Apr 2026
Brief summary (registry, in English)
Bright light therapy has been shown to be effective for the treatment of both seasonal and non-seasonal unipolar depression as well as bipolar depression, primarily in outpatients under the age of 60. There is a dearth of studies exploring the efficacy of this treatment modality among elderly depressed inpatients, which is our study population.
- Status (registry)
- Enrolling by invitation
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 6 May 2025
- Start date
- 14 Nov 2025
- Primary completion date
- 30 Jun 2027
- Lead sponsor
- Medical University of South Carolina
- Diseases
- Depression
- NCT number
- NCT07002554
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 20
- From 14 Nov 2025 to the primary completion date, 30 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Any prior use of bright light therapy
- Treatment with ECT; if a patient's condition deteriorates during study participation such that the treatment team feels ECT would be in their best interest, they will be withdrawn from study participation. For logistical and transport purposes, the study team feels that exclusion of patients receiving ECT will be necessarily. Additionally, these patients would likely be excluded from a future larger RCT given that ECT would likely interfere with signal of BLT efficacy.
Other illness
- Primary indication for hospitalization is for a disorder other than major depressive disorder (determined by patient's treatment team)
- Photosensitive medical conditions or current use of photosensitizing medications - if patients have been advised by a treating clinician at any point to avoid sunlight because of their current medication regimen or medical condition, they will be considered to have a photosensitive medical condition and will be excluded from this study.
- Major neurocognitive disorder
Other
- Uncontrolled headaches or any migraines within the last month
- Severe intellectual disability
- Inability to consent for the study
- Active psychosis
- Inmates
Who the study is looking for
- A current episode of non-psychotic unipolar depression as the primary reason for psychiatric hospitalization
- Currently hospitalized on the MUSC Senior Care Unit
- Age 60 years or older
- HAMD-17 ≥8
Age in the registry: 60 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical University of South Carolina Institute of Psychiatry Senior Care Unit Coordinator of this site? Confirm its status | Charleston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.