NCT07002788Active, not recruiting
Comparison Paravertebral and Serratus Anterior Plane Block in Video-assisted Thoracoscopic Surgery.
Comparison of Postoperative Analgesic Efficacy of Paravertebral Block and Serratus Anterior Plane Block in Patients Undergoing Video-assisted Thoracoscopic Surgery (VATS)
Source: ClinicalTrials.gov · Last updated 4 Jun 2025
Brief summary (registry, in English)
Video-assisted thoracoscopic surgery (VATS) is a minimally invasive alternative to thoracotomy that emerged in the early 1990s, aiming to reduce surgical stress and postoperative pain. While VATS generally results in less pain than thoracotomy, patients may still experience significant discomfort. Effective pain control remains crucial in VATS to minimize postoperative complications, especially pulmonary and cardiac events, which can arise from inadequate ventilation and impaired sputum clearance due to pain. Various strategies have been developed to manage postoperative pain, with multimodal approaches-combining regional or peripheral blocks with systemic analgesics such as NSAIDs and adjuvants-now considered standard. Among regional techniques, serratus anterior plane (SAP) block and thoracic paravertebral block (PVB) are commonly used. SAP block targets the thoracodorsal, long thoracic, and T2-T9 spinal nerves between the latissimus dorsi and serratus anterior muscles, providing effective anterolateral chest wall analgesia. PVB targets intercostal nerves within the paravertebral space and has shown superior pain control and improved lung function compared to systemic opioids or intrapleural local anesthetics. At our center, both SAP and PVB are routinely used for postoperative analgesia in VATS procedures for patients with lung masses. Pain levels will be assessed using the Visual Analog Scale (VAS), a reliable tool for evaluating both acute and chronic pain, unaffected by age or gender. This study aims to compare the effectiveness of SAP and PVB blocks in terms of postoperative pain, opioid requirements, and block-related complications in patients undergoing VATS under general anesthesia. The research is observational and will not alter routine clinical practices.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 122 (actual)
- First submitted
- 16 Mar 2025
- Start date
- 1 Dec 2024
- Primary completion date
- 1 Dec 2025
- Lead sponsor
- Hacettepe University
- Diseases
- Lung cancer
- NCT number
- NCT07002788
What you commit to
- Study type: Interventional
- Participants enrolled: 122
- From 1 Dec 2024 to the primary completion date, 1 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Those with renal failure,
- Those with liver failure,
- Those with local anesthetic allergy,
- Those with infection in the area where the procedure will be performed,
Other
- Those with neuropathy,
- Those with coagulopathy,
- Those with congenital muscle absence in the area where the block will be performed
- Patients who did not give consent to participate in the study
Who the study is looking for
- Patients between the ages of 18-64 who gave consent to participate in the study
- Patients between the ages of 65-90 who received a score of 24 or more from the mini mental test and gave consent to participate in the study
- ASA 1-3 patients
Age in the registry: 18 years to 90 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hacettepe Üniversitesi Coordinator of this site? Confirm its status | Ankara | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.