NCT07003867Completed
Ventilator Inspiratory Trigger Sensitivity Adjustment Versus Threshold Device Training on Pulmonary Functions in Acute Stroke Patients
Source: ClinicalTrials.gov · Last updated 19 Nov 2025
Brief summary (registry, in English)
Neurological dysfunction is a common condition necessitating prolonged mechanical ventilation (PMV). Among patients with acute neurological diseases, 17% to 33% are intubated and mechanically ventilated for respiratory failure. Patients with acute neurological diseases requiring MV generally have adverse outcomes with a hospital mortality rate among patients with such diseases has been reported to be in the range of 16-33%. Inspiratory muscle weakness is common in patients receiving mechanical ventilation, especially patients with prolonged duration of mechanical ventilation. Inspiratory muscle training could limit or reverse these unhelpful squeal and facilitate more rapid and successful weaning.Hence, the importance of physical therapy emerged in helping patients to be weaned from ventilators by using various methods to strengthen the respiratory muscles in different ways.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 40 (actual)
- First submitted
- 23 May 2025
- Start date
- 10 Jun 2025
- Primary completion date
- 15 Aug 2025
- Lead sponsor
- Al-Zaytoonah University of Jordan
- Diseases
- Stroke
- NCT number
- NCT07003867
What you commit to
- Study type: Interventional
- Participants enrolled: 40
- From 10 Jun 2025 to the primary completion date, 15 Aug 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Persistent hemodynamic instability as life threatening arrhythmias, acute heart failure, angina.
- Any progressive neuromuscular disease that would interfere with responding to inspiratory muscle training.
Other
- Severe breathlessness when spontaneously breathing.
- Spinal cord injuries.
- Skeletal pathology (scoliosis, flail chest, spinal instrumentation) that would seriously impair the movement of the chest wall and ribs.
- Patients on heavy sedation and respiratory muscle paralysis
Who the study is looking for
- Adults aged 40-60 years.
- Diagnosed with acute stroke patients.
- Body mass index (BMI) 18:35 kg/m².
- conscious oriented patients with Glasgow coma score ≥ 13.
- PH\>7.25 and arterial oxygen saturation \>90%
Age in the registry: 40 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mohamed Saied Zidan Coordinator of this site? Confirm its status | Cairo | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.