NCT07004790Not yet recruiting
Prognostic Value of Transcranial Doppler Ultrasound in the Clinical Evolution of Patients With Acute Ischemic Stroke. The TRADE-AIS Study
Prognostic Value of Transcranial Doppler Ultrasound in the Clinical Evolution of Patients With Acute Ischemic Stroke: A Prospective Observational Study
Source: ClinicalTrials.gov · Last updated 16 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This prospective observational study aims to determine whether specific parameters measured by transcranial Doppler ultrasound (TCD) can predict clinical outcomes in patients with acute ischemic stroke (AIS). The primary objective is to evaluate the association between middle cerebral artery (MCA) flow velocities and short-term neurological improvement. Secondary outcomes include the presence of collateral flow and flow patterns in relation to functional recovery measured by NIHSS and modified Rankin Scale (mRS) scores.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- First submitted
- 27 May 2025
- Start date
- 1 Aug 2026
- Primary completion date
- 31 Jul 2027
- Lead sponsor
- Jose Ivan Rodriguez de Molina Serrano
- Diseases
- Stroke
- NCT number
- NCT07004790
What you commit to
- Study type: Interventional
- Planned participants: 50
- From 1 Aug 2026 to the primary completion date, 31 Jul 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Intubated or hemodynamically unstable prior to Doppler evaluation
Other illness
- Evidence of intracerebral hemorrhage on imaging
- Known diagnosis of neurodegenerative disease significantly affecting baseline neurological function (e.g., advanced dementia, Parkinson's disease)
Other
- Inadequate temporal acoustic window for transcranial Doppler
- Refusal to participate or withdrawal of consent
Who the study is looking for
- Age ≥ 18 years
- Clinical diagnosis of acute ischemic stroke
- Onset of symptoms ≤ 24 hours before admission
- Underwent or will undergo transcranial Doppler ultrasound within 24 hours of symptom onset
- Able to provide informed consent or consent obtained from a legal representative
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.