NCT07006935Recruiting
REACH Study (Recovery Environments: Assessing Cognitive & Brain Health in Community Mental Health)
Pilot Study of the Cognitive and Neurobiological Effects of the Clubhouse Model of Psychosocial Rehabilitation for Schizophrenia and Related Conditions
Source: ClinicalTrials.gov · Last updated 4 Nov 2026
Brief summary (registry, in English)
The purpose of this study is to understand how different types of community-based mental health care affect thinking abilities, daily functioning, and brain activity in adults with schizophrenia and related conditions. The investigators are especially interested in learning whether the Clubhouse Model-a structured, supportive community for individuals with mental illness-has unique benefits compared to standard outpatient mental health services. If participants decide to join, they will be asked to complete a total of six study visits with the research team over the course of your participation. Three of these study visits are at the beginning (baseline) and the remaining three are six months later. Two of the three visits will includes interviews, questionnaires, and thinking and memory tasks (cognitive testing) and one session will be an MRI brain scan, which is a safe and non-invasive imaging procedure. The total time required for each visit will be approximately 90 minutes to two hours. Participants may take breaks as needed.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 28 May 2025
- Start date
- 1 Sept 2026
- Primary completion date
- 30 Jan 2028
- Lead sponsor
- Case Western Reserve University
- Diseases
- Schizophrenia
- NCT number
- NCT07006935
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 1 Sept 2026 to the primary completion date, 30 Jan 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- (1) had previous membership at a Clubhouse (Magnolia or elsewhere)
Other illness
- (2) have a current severe substance use disorder
- (4) a co-occurring diagnosis of an intellectual or learning disability or neurodevelopment condition (e.g., Autism; based on chart review)
- (5) had recent psychiatric instability requiring hospitalization in the past month;
- (6) history of a traumatic brain injury (TBI; based on record review)
Other
- (3) have persistent suicidal or homicidal behavior
- (7) contraindicators for MRI (e.g., pacemaker, claustrophobia)
- Participants in the usual care will be excluded if they are a current Clubhouse member or join a Clubhouse during participation in this research
Who the study is looking for
- (1) have a DSM-V diagnosis of schizophrenia, schizoaffective disorder, or schizophreniform confirmed by diagnostic assessment and medical record review
- (2) between the ages of 18-50
- (3) stabilized on psychotropic medication as indicated by no changes to the primary psychiatric medication in the last month
- (4) able to read and speak fluent English at a sixth grade level or higher for purposes of informed consent and cognitive testing
- For Clubhouse members, they must be a first-time, newly enrolled member
Age in the registry: 18 years to 50 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Case Western Reserve University Coordinator of this site? Confirm its status | Cleveland | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.