NCT07008274Completed
Laparoscopic Sleeve Gastrectomy-Induced Decline in Plasma Asprosin and Its Association With Metabolic Recovery
Source: ClinicalTrials.gov · Last updated 6 Jun 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
the present study aimed to systematically assess the changes in plasma asprosin levels at 3, 6, and 12 months after LSG, to explore the relationships between asprosin dynamics and key metabolic parameters, including body mass index (BMI), fasting glucose, insulin resistance assessed by the homeostasis model (HOMA-IR), and lipid profiles, and to compare asprosin concentrations between bariatric patients and healthy normal-weight controls.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 85 (actual)
- First submitted
- 11 May 2025
- Start date
- 1 Jan 2021
- Primary completion date
- 31 Jan 2025
- Lead sponsor
- Northern Jiangsu People's Hospital
- Diseases
- Obesity
- NCT number
- NCT07008274
What you commit to
- Study type: Observational
- Participants enrolled: 85
- From 1 Jan 2021 to the primary completion date, 31 Jan 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- history of prior bariatric or gastrointestinal surgery;
Other illness
- active malignancy, chronic inflammatory or infectious disease, or severe hepatic or renal dysfunction;
Other
- pregnancy during the study period;
- incomplete clinical or biochemical data.
Who the study is looking for
- age between 18 and 65 years;
- body mass index (BMI) ≥37.5 kg/m², or BMI ≥32.5 kg/m² with at least one obesity-related comorbidity;
- availability of complete clinical data and stored plasma samples at preoperative baseline and at 3, 6, and 12 months postoperatively.
Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Shuai Zhao Coordinator of this site? Confirm its status | Yangzhou | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.