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NCT07011329Active, not recruiting

Brain Alterations Based on Multiplex MR Imaging in Nasopharyngeal Carcinoma Patients After Treatment, and Their Correlation With Clinical Cognitive Scores.

Brain Alterations Detected by Multiplex MR Imaging in Nasopharyngeal Carcinoma Patients After Treatment

Source: ClinicalTrials.gov · Last updated 11 Jun 2025

Brief summary (registry, in English)

The objective of this study is to examine the potential impact of the treatment before, during, and/or after radiotherapy on the brain in patients with nasopharyngeal carcinoma (NPC) using Multiplex (MTP) MR imaging sequence, which generate multiple contrasts with one-time scan. We aimed to investigate the altered MTP parameters and their correlation with clinical cognitive scores before and after the treatment.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
60 (estimated)
First submitted
30 May 2025
Start date
1 Apr 2023
Primary completion date
31 Dec 2025
Lead sponsor
Hubei Cancer Hospital
NCT number
NCT07011329

What you commit to

  • Study type: Observational
  • Planned participants: 60
  • From 1 Apr 2023 to the primary completion date, 31 Dec 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • any current medications that may affect cognitive function

Other illness

  • brain tumor or atrophy, neural-associated diseases, a history of brain surgery

Other

  • brain invasion
  • inability to attend MRI scanning

Who the study is looking for

  • pathological evidence of NPC (stages III-IV at diagnosis according to the 8th edition of the UICC/AJCC staging system for NPC)
  • right-handed
  • prepared to receive treatments
  • prepared to receive the Montreal Cognitive Assessment (MoCA)

Age in the registry: 30 years to 80 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Department of Radiology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology
Coordinator of this site? Confirm its status
WuhanChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.