NCT07011914Recruiting
Care in Multiple Sclerosis (MS)
CARE in MS: Childhood Adversity Research Effort in MS
Source: ClinicalTrials.gov · Last updated 26 Oct 2026
Brief summary (registry, in English)
This study is structured around three main aims. In Aim 1, investigators will conduct community-based participatory research (CBPR) to develop culturally tailored methods to assess childhood adversity in multiple sclerosis (MS). Aim 2 will investigate the impact of childhood adversity on MS outcomes among individuals with relapsing-remitting MS (RRMS), among whom 70% belong to a group historically under-represented in MS research: Black, Hispanic, or poverty-impacted. Aim 2 procedures involve two visits that include a research blood draw and an MRI scan. In Aim 3, investigators will conduct interviews and surveys to explore environmental and social factors affecting quality of life for minority MS patients.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 2 Jun 2025
- Start date
- 23 Oct 2025
- Primary completion date
- 30 Jun 2029
- Lead sponsor
- NYU Langone Health
- Diseases
- Multiple sclerosis
- NCT number
- NCT07011914
What you commit to
- Study type: Observational
- Planned participants: 300
- From 23 Oct 2025 to the primary completion date, 30 Jun 2029
- 6 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- MS relapse within 30 days prior to study entry
Other illness
- Other major neurologic or psychiatric illness
Other
- Primary or Secondary Progressive MS
- Inability to consent.
Who the study is looking for
- Aim 1 -
- aged ≥18-29 years
- diagnosis of RRMS (Fulfill international criteria for relapsing remitting (RRMS))
- 70% self-identifying as a Black, Hispanic, or poverty-impacted (up to 138% of the federal poverty level) individual,and
- fluent in English or Spanish.
- Aim 2 -
- aged ≥18-29 years
- diagnosis of RRMS (Fulfill international criteria for relapsing remitting (RRMS))
- 70% self-identifying as a Black, Hispanic, or poverty impacted, and
- fluent reading in English or Spanish
- Pediatric onset MS (MS onset before age 18 and age at time of enrollment is 18-25) OR adult-onset MS (MS onset at age 18 or older and age at time of enrollment is 19-29)
- Disease duration below 8 years
- Aim 3 -
- Aim 3 will enroll the first 20 participants from Aim 2 who meet the following criteria:
- completed at least 80% of study data in the cross-sectional study/Aim 2.
- a total of 70% must self-identify as Black, Hispanic, or meet criteria for poverty impacted.
- interviews will be evenly split between participants with high (top quartile) and low (bottom quartile) of PROMIS-10 scores.
Age in the registry: 18 years to 29 years · Sex: All · Does not accept healthy volunteers
Sites (6)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Colorado Denver Coordinator of this site? Confirm its status | Aurora | United States | Recruiting |
| University of Alabama at Birmingham Coordinator of this site? Confirm its status | Birmingham | United States | Recruiting |
| Massachusetts General Hospital Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
| Cleveland Clinic Coordinator of this site? Confirm its status | Cleveland | United States | Recruiting |
| Baylor College of Medicine Coordinator of this site? Confirm its status | Houston | United States | Recruiting |
| University of California San Francisco Coordinator of this site? Confirm its status | San Francisco | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.