NCT07012226Completed
Comparison of Cardiometabolic Markers in Individuals With Hypertriglyceridemia With Low and High Weight Loss Responses to an Energy-restricted Diet
Effects of an Energy-restricted Diet on the Expression of the Sirtuin-1 and Leptin Receptor Genes in White Blood Cells, and Cardiometabolic Markers in Individuals With Hypertriglyceridemia: Comparison Between Low and High Weight Loss Responders
Source: ClinicalTrials.gov · Last updated 28 Jan 2026
Brief summary (registry, in English)
Total RNA is extracted from isolated white blood cells, and cDNA is synthesized from these samples. Subsequently, the expression levels of the SIRT1 and leptin receptor genes are determined through quantitative PCR.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 27 May 2025
- Start date
- 10 Jun 2025
- Primary completion date
- 12 Jan 2026
- Lead sponsor
- Shahid Beheshti University of Medical Sciences
- Diseases
- Obesity
- NCT number
- NCT07012226
What you commit to
- Study type: Interventional
- Participants enrolled: 60
- From 10 Jun 2025 to the primary completion date, 12 Jan 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Any change in the treatment plan during the study, including changes in the type and dose of medications taken or the start of medications that affect blood lipids
Other illness
- Advanced chronic kidney disease patients
Other
- Patients with liver cirrhosis
- Unwillingness to continue cooperating with the study
Who the study is looking for
- Mild to moderate hypertriglyceridemia (TG=150-500 mg/dL)
- Body mass index (BMI) greater than 25
- Not using fibrates
Age in the registry: 18 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Nutrition Clinic located in the Faculty of Nutrition Sciences, Shahid Beheshti University of Medical Sciences Coordinator of this site? Confirm its status | Tehran | Iran | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.