NCT07013409Completed
Probiotics' Effects on Hormones, Body and Mood in Obese Women
Safety and Efficacy of Lacticaseibacillus Rhamnosus LRa05, Lactobacillus Crispatus LCr86 and Limosilactobacillus Reuteri LR08 on Hormone Metabolism, Body Composition, and Emotional Regulation in Overweight Women
Source: ClinicalTrials.gov · Last updated 6 Jul 2026
Brief summary (registry, in English)
To evaluate the regulatory effect of probiotics formula on visceral fat metabolism and sex hormone balance in obese women.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 102 (actual)
- First submitted
- 2 Jun 2025
- Start date
- 8 Jul 2025
- Primary completion date
- 30 Sept 2025
- Lead sponsor
- Wecare Probiotics Co., Ltd.
- Diseases
- Obesity
- NCT number
- NCT07013409
What you commit to
- Study type: Interventional
- Participants enrolled: 102
- From 8 Jul 2025 to the primary completion date, 30 Sept 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Have received/are currently receiving treatment for the following mental illnesses: alcohol/drug/substance abuse dependence, schizophrenia, psychosis, bipolar disorder.
- Take medication for depression or low mood.
- Have received radiotherapy or chemotherapy in the past.
- Have received general anesthesia surgery/procedures within the past three years, or plan to receive general anesthesia procedures/surgeries within the next three months during this trial.
Other illness
- Suffering from digestive system diseases, mainly gastrointestinal diseases (celiac disease, ulcerative colitis, Crohn's disease).
- Suffering from severe neurological disorders (epilepsy, stroke, severe head trauma, meningitis within the past 10 years, brain surgery, brain tumor, long-term coma - excluding general anesthesia).
- Suffering from internal organ failure (such as heart, liver or kidney failure, etc.).
- Have suffered from hepatitis (hepatitis B, hepatitis C), HIV or syphilis in the past.
Who the study is looking for
- Age: 18 to 40 years old, female, BMI ≥ 25 kg/m2.
- Be willing to receive follow-up during the intervention period.
- Be willing to provide two blood, urine and fecal samples during the intervention period.
- Be willing to take the compound probiotics by oneself every day during the intervention period.
- Have good hearing and be able to hear and understand all instructions during the intervention period.
Age in the registry: 18 years to 40 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The First Affiliated Hospital of Zhengzhou University Coordinator of this site? Confirm its status | Zhengzhou | China | Unknown status |
Related publications
- Safety and efficacy of Lacticaseibacillus rhamnosus LRa05, Limosilactobacillus reuteri LR08, and Lactobacillus crispatus LCr86 on hormone metabolism, body composition, and emotional regulation in overweight women: a randomized, double - blind, placebo - controlled trial.J Appl Microbiol · 2026 · PMID 42731127
This page is information, not medical advice. Discuss any trial with your doctor.