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NCT07013942Completed

Additional Effects of Dry Needling With PNF on Spasticity and Functional Performance in Stroke

Source: ClinicalTrials.gov · Last updated 10 Jun 2025

Brief summary (registry, in English)

Stroke is a prevalent cause of long-term disability, with a rising global incidence. Stroke patients commonly experience impaired balance and trunk control, which limits their daily activities and quality of life. Spasticity is the result of upper motor neuron lesion in which the reflex arc is spared, however there is a lesion to the descending pathways of the spinal cord, which leads to the hyper excitability of the alpha motor neurons. Spasticity is a form of velocity dependent hypertonia. When dry needle is applied it induces relaxation in the muscle by increasing the distance between the z lines in the sarcomere and reduces the overlapping of contractile proteins, which ultimately leads to relaxation in the muscle. Dry needling also reduces the firing of the afferent pathways from the local muscle to the spinal cord reducing the excitability of the alpha motor neurons this leads to reduce spasticity. A randomized control trial will be conducted in multidisciplinary lab of FUCP, department of physical medicine and rehabilitation of Fauji Foundation Hospital on the sample of 30 participants. The subjects will be randomized into two groups by sealed opaque envelope method. A treatment over the course of 6 weeks will be provided. Interventional group will be receiving dry needling in addition to Proprioceptive Neuromuscular Facilitation while the control group will receive sham needling in addition to Proprioceptive Neuromuscular Facilitation. Exercise training would be done for a total of 6 weeks, with needling twice a week, the session will last 30- 50 minutes. Using SPSS version 21 would do analysis. Ethical approval will be obtained from ERC of FUSH. Informed written consent will be obtained from all participants.

Status (registry)
Completed
Study type
Interventional
Enrollment
30 (actual)
First submitted
2 Jun 2025
Start date
12 Sept 2024
Primary completion date
15 Mar 2025
Lead sponsor
Foundation University Islamabad
Diseases
Stroke
NCT number
NCT07013942

What you commit to

  • Study type: Interventional
  • Participants enrolled: 30
  • From 12 Sept 2024 to the primary completion date, 15 Mar 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Patients with underlying infections
  • Patients with autoimmune diseases
  • Patients that have any contagious conditions

Other

  • Non-compliant Diabetic patients
  • Active Hypertensive patients
  • Immuno compromised patients

Who the study is looking for

  • 18 years to 65 years of age.
  • Males and females
  • Post stroke spasticity
  • Ischemic stroke

Age in the registry: 60 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Foundation University College of Physical Therapy
Coordinator of this site? Confirm its status
IslamabadPakistanUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.