NCT07018128Completed
Expression of Genes Relating Hypertension and Efficacy of 4-7-8 Breathing Control on Reducing Blood Pressure
Expression of Genes Relating Hypertension in Thailand and the Efficacy of 4-7-8 Breathing Control on Reducing Blood Pressure in Individuals With Hypertension
Source: ClinicalTrials.gov · Last updated 8 Oct 2026
Brief summary (registry, in English)
This study consists of two sub-studies. Study 1 investigates gene expression related to the development of hypertension in Thailand, and Study 2 examines the effectiveness of the 4-7-8 breathing technique in reducing blood pressure in individuals with hypertension.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 225 (actual)
- First submitted
- 1 Jun 2025
- Start date
- 1 Oct 2024
- Primary completion date
- 31 Mar 2026
- Lead sponsor
- Burapha University
- Diseases
- High blood pressure
- NCT number
- NCT07018128
What you commit to
- Study type: Interventional
- Participants enrolled: 225
- From 1 Oct 2024 to the primary completion date, 31 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Is currently pregnant, breastfeeding, or has a history of pregnancy within the 6 months prior to participating in the study
Other illness
- Has heart disease, such as valvular stenosis or regurgitation, coronary artery disease, or heart failure
- Has a fever or is currently experiencing an infectious disease, such as COVID-19, the flu, or other infections
- Has heart disease, such as valvular stenosis or regurgitation, coronary artery disease, or heart failure
- Has a fever or is currently experiencing an infectious disease, such as COVID-19, the flu, or other infections
- Study 2:
- Has respiratory diseases, cardiovascular diseases, cerebrovascular disease, kidney disease, cancer, or immune-related conditions such as allergies, autoimmune diseases (e.g., SLE), immunodeficiency, or rheumatoid arthritis
- Has a fever or is currently infected, such as with COVID-19, the flu, or other infectious diseases
Other
- Has obesity, defined as having a body mass index (BMI) of 30 kg/m² or higher
- Group of individuals with normal blood pressure
- Has obesity, defined as having a body mass index (BMI) of 30 kg/m² or higher
- Is obese, defined as having a body mass index (BMI) of 30 kg/m² or higher
Who the study is looking for
- Male or female
- Aged between 18-59 years
- Of Thai ethnicity
- Diagnosed with hypertension, defined as having an SBP of 140 mmHg or higher, or a DBP of 90 mmHg or higher, or having previously been diagnosed with hypertension and currently taking antihypertensive medication
- Originally from various regions of Thailand and currently residing in the eastern region
- Male or female
- Aged between 18-59 years
- Of Thai ethnicity
- Does not have hypertension, defined as having an SBP below 130 mmHg and a DBP below 85 mmHg, with no prior diagnosis of hypertension and no history of taking antihypertensive medication
- Originally from various regions of Thailand and currently residing in the eastern region
- Male or female, aged 35-59 years
- Diagnosed with hypertension, with blood pressure levels above the normal range, defined as SBP of 130 mmHg or higher, or DBP of 85 mmHg or higher, and currently taking medication
- Originally from various regions of Thailand and currently residing in the eastern region
- Able to communicate effectively
Criteria the registry did not label
- Study 1:
- Group of individuals with hypertension
Age in the registry: 18 years to 59 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Faculty of Allied Health Sciences, Burapha University Coordinator of this site? Confirm its status | MueangChonburi | Thailand | Unknown status |
Related publications
- Visceral Adiposity Is Independently Associated with Hypertension in Thai Adults: A Case-Control Study.Int J Environ Res Public Health · 2026 · PMID 42652372
This page is information, not medical advice. Discuss any trial with your doctor.