NCT07023770Recruiting
Rehabilitation Program Dedicated to Post-stroke Lateropulsion Including Exoskeleton Assisted Exercises
Source: ClinicalTrials.gov · Last updated 1 Sept 2026
Brief summary (registry, in English)
Lateropulsion is a deficit in the body orientation with respect to the vertical in the coronal plane, defined by the presence of one of the three signs: lateral body tilt, active pushing from the sound limbs, and resistance to passive corrections. The lateral body tilt is the cardinal sign, the frequency of the 2 other signs increasing with lateropulsion severity (most dramatic forms called pusher syndrome in the past). Lateropulsion is frequent after stroke, and represents the main factor underpinning balance and gait disorders at the subacute phase. After hemisphere stroke lateropulsion is caused by a bias in the internal model of the verticality in the frontal plane, individuals unconsciously aligning their body posture on a tilted verticality representation. Pilot studies suggested the possibility to recalibrate the internal model of verticality, biased by stroke, and to improve individuals' uprightness. The investigators expect that a specific rehabilitation program combining technics devoted to lateropulsion, and comprising exoskeleton (Atalante) assisted balance exercises could help recalibrate the internal model of verticality and alleviate lateropulsion. The primary objective is to test the hypothesis that a 3-week specific lateropulsion rehabilitation program (15 sessions of 30 minutes including exoskeleton and a rehabilitation focused on the vertical body orientation in the frontal plane) improves the visual vertical (VV), the most used test to assess verticality perception.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 3 (estimated)
- First submitted
- 22 Apr 2025
- Start date
- 18 Nov 2025
- Primary completion date
- 30 Sept 2026
- Lead sponsor
- University Hospital, Grenoble
- Diseases
- Stroke
- NCT number
- NCT07023770
What you commit to
- Study type: Interventional
- Planned participants: 3
- From 18 Nov 2025 to the primary completion date, 30 Sept 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Comprehension or cognitive or behavioral disorders, or depressive symptoms that compromise participation in the program
- Postural disorders or body geometry disorders that interfere with balance for a reason that is independant of the stroke
- History of osteoporotic fractures.
Other
- Medical instability making evaluation impossible,
- Morphological contraindications to the use of the Atalante® robot (segment length or joint ranges; height \<155cm; weight \>100kg),
- Severe spasticity (\>3 on the modified Ashworth scale) in the adductors, quadriceps, hamstrings and triceps surae
- Presence of a pressure sore at the areas of contact with the Atalante® robot,
- Pregnancy and breastfeeding
Who the study is looking for
- Right hemispheric first and unique ischemic stroke between 2 weeks and 6 months old (subacute phase) ;
- Presence of lateropulsion, assessed by the Scale for Contraversive Pushing (2 ≤ SCP \< 5)
- Presence of contralesional VV bias (VV \> 4°)
- Right handedness defined by a Edinburgh score ≥0,39
- Being hospitalized in a Physical Medicine and Neurological Rehabilitation (PMR) facility.
- Have given a written and informed consent
Age in the registry: 18 years to 84 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Grenoble University Hospital Coordinator of this site? Confirm its status | Échirolles | France | Recruiting |
| Grenoble University Hospital Coordinator of this site? Confirm its status | Grenoble | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.