NCT07024433Recruiting
Tubeless Anesthesia in Preventing Lung Complications in Patients Undergoing Surgery for Early-Stage Lung Cancer
Tubeless Anesthesia in Preventing Contralateral Lung Complications in Patients Undergoing Single-Port Thoracoscopic Surgery for Early-Stage Lung Cancer: A Single-Center, Prospective, Open-Label, Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 17 Jun 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The study focuses on evaluating the effectiveness and safety of tubeless anesthesia in single-port thoracoscopic surgery for early-stage lung cancer patients. Traditional anesthesia methods risk postoperative complications like lung injury and respiratory issues. Tubeless anesthesia preserves spontaneous breathing without tracheal intubation, potentially reducing these complications and enhancing recovery. The study aims to compare this technique with traditional methods, assessing its impact on contralateral lung complications, perioperative hemodynamics, complication rates, and recovery speed.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 224 (estimated)
- First submitted
- 29 May 2025
- Start date
- 25 May 2025
- Primary completion date
- 1 May 2026
- Lead sponsor
- Fujian Medical University Union Hospital
- Diseases
- Lung cancer
- NCT number
- NCT07024433
What you commit to
- Study type: Interventional
- Planned participants: 224
- From 25 May 2025 to the primary completion date, 1 May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients expected to have extensive pleural adhesions or with previous lung resection;
- Previous induction chemotherapy or chemoradiotherapy;
- Patients expected to have large surgical wounds and lengthy procedures, clinically assessed as unsuitable;
Other illness
- Patients whose cardiac and pulmonary function, or overall health, cannot withstand the procedure.
Other
- Obese patients (BMI \>30);
- Patients with difficult intubation or expected complex airway management;
- COPD patients with copious airway secretions;
- Patients with neurological dysfunction or who cannot cooperate while awake;
- Elderly and frail patients with severe hypoxia (PaO2 \<60 mmHg) or hypercapnia (PaCO2 \>50/55 mmHg);
- Intraoperative need to isolate the lung to prevent spillage and contamination of the contralateral lung;
Who the study is looking for
- Age ≥18 years and ≤70 years;
- ECOG performance status score 0-1;
- Good cardiac and pulmonary function;
- Single or multiple peripheral lung nodules planned for single-port thoracoscopic surgery, with or without mediastinal lymph node dissection or sampling;
- Able to comply with the study visit schedule and other protocol requirements;
- Signed informed consent and voluntary participation in the study.
Age in the registry: 18 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fujian Medical University Union Hospital Coordinator of this site? Confirm its status | Fuzhou | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.