NCT07024511Not yet recruiting
Effectiveness of Auricular Acupuncture for Migraine
Source: ClinicalTrials.gov · Last updated 17 Jun 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Migraine is a primary headache disorder characterized by recurrent episodes of moderate to severe pain, frequently accompanied by nausea, photophobia, and phonophobia. It ranks as the third most prevalent medical condition globally and is recognized by the World Health Organization (WHO) as one of the top ten causes of disability worldwide. Migraine presents substantial public health concerns due to its considerable socioeconomic burden and its detrimental impact on individuals' quality of life. Although pharmacological treatments are widely available, their effectiveness is often limited, with many patients experiencing inadequate symptom relief or adverse side effects. Consequently, there has been growing interest in non-pharmacological approaches, particularly acupuncture and auricular therapy, due to their favorable safety profiles and reported efficacy in alleviating migraine symptoms. Auricular therapy, a microsystem of acupuncture applied to specific points on the external ear, has gained popularity for its simplicity, low risk, and therapeutic potential. Despite its increasing clinical use, robust scientific evidence supporting the effectiveness of auricular therapy for migraine remains insufficient, underscoring the need for well-designed clinical studies to validate its therapeutic value.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 156 (estimated)
- First submitted
- 23 May 2025
- Start date
- 1 Jul 2025
- Primary completion date
- 31 Dec 2025
- Lead sponsor
- Universiti Tunku Abdul Rahman
- Diseases
- Migraine
- NCT number
- NCT07024511
What you commit to
- Study type: Interventional
- Planned participants: 156
- From 1 Jul 2025 to the primary completion date, 31 Dec 2025
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of psychotic disorder(s).;
- Severe somatic disorder(s);
- History of severe organic psychiatric disorder(s);
- History of other chronic pain condition(s) in the pass 3 months;
- History of addictive disorder(s);
Other
- All other diagnoses of chronic, tension-type headache, cluster headache and/or secondary headaches;
- Pregnancy or lactation;
- Visual Aura Rating Scale, VARS≥5 score;
- Taking long-term painkillers for more than 1 month within 3 months.
Who the study is looking for
- Diagnosed as having migraine with aura and without aura according to the diagnostic criteria specified by the ICHD 3;
- Aged between 18 and 65 years old;
- Provided written informed consent;
- Headache lasting for 4 to 72 hours and occur at least 5 times (untreated or poorly treated);
- At least 2 out of 4 criteria must be met (unilateral, pulsatile, moderate to severe pain, headache aggravated by daily physical activity, or avoidance of daily activities such as walking or climbing stairs due to headache);
- At least one of the two criteria must be met (nausea and/or vomiting, photophobia, and fear of sound);
- At least one fully recoverable premonitory symptom (visual, sensory, speech and/or language, motor, brainstem, retina); Onset time more than 5 minutes; (8) No prophylaxis treatments with acupuncture or drugs in the past 3 months; (9) Written informed consent provided.
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hebei University of Engineering Affiliated Hospital Coordinator of this site? Confirm its status | Handan | China | Unknown status |
| Yurangqiao Community Health Service Center, Xingdong New District, Xingtai City Coordinator of this site? Confirm its status | Xingtai | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.