NCT07024992RecruitingPhase 2
Enhancing Smoking Cessation for African American People Everywhere
A National Test of a Culturally Tailored Smartphone-based Smoking Cessation and Mental Health Intervention for Black Adults With HIV
Source: ClinicalTrials.gov · Last updated 13 Jul 2026
Brief summary (registry, in English)
The present study aims to investigate the efficacy of an mHealth smoking cessation and HIV disease management intervention among a nationally representative sample of African America/Black (hereafter refer to as Black) persons with HIV/AIDS (PWH) who smoke cigarettes. Participants will be randomized into one of three conditions: (1) the intervention, ESCAPE (Enhancing Smoking Cessation for African American People Everywhere) + Nicotine Replacement Medications (NRT), (2) the National Cancer Institute's (NCI) quitSTART app, the standard mobile smoking cessation treatment + NRT, and (3) an assessment-only control group + NRT.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 300 (estimated)
- First submitted
- 5 May 2025
- Start date
- 30 Jun 2026
- Primary completion date
- 30 Jun 2029
- Lead sponsor
- University of Houston
- Diseases
- HIV
- NCT number
- NCT07024992
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 300
- From 30 Jun 2026 to the primary completion date, 30 Jun 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Having experienced a heart attack within the past 2 weeks
Other
- Legal situations which may interfere with study participation
- Not being fluent in English
- High blood pressure that is not under control
- Pregnant of planning to become pregnant within the next six months
Who the study is looking for
- At least 18 years of age
- Identify as Black/African American
- Living with HIV
- Biochemical verification of self-reported smoking status following minimum study specified smoking rate endorsement
- Motivated to quit smoking
- Must be ready to quit cigarettes within 14 days of full enrollment
- Moderate or higher anxiety sensitivity OR elevated anxiety OR depression
- Must be willing to download a mobile app onto their personal phone
- Must be willing to use NRT
- Possess an Android/Apple smartphone that is compatible with the mobile app
- Demonstrate 7th grade level proficiency in English (≥4 on the Rapid Estimate of Adult Literacy in Medicine-Short Form \[REALM-SF\])
- Valid proof of identification (photo of valid US ID)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Oklahoma Health Sciences Center Coordinator of this site? Confirm its status | Oklahoma City | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.