NCT07026864Not yet recruiting
MRI-Guided Bladder Preservation Program For Patients With Muscle Invasive Bladder Cancer
Project #1: MRI-guided Bladder Cancer Preservation Program
Source: ClinicalTrials.gov · Last updated 24 Aug 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this clinical trial is to learn if the use of MRI-guided irradiation increases the rates of bladder preservation as well as to decrease complications in patients with muscle invasive bladder cancer who wish to retain their bladders
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 31 (estimated)
- First submitted
- 10 Jun 2025
- Start date
- Oct 2025
- Primary completion date
- Jul 2030
- Lead sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
- Diseases
- Bladder cancer
- NCT number
- NCT07026864
What you commit to
- Study type: Interventional
- Planned participants: 31
- From Oct 2025 to the primary completion date, Jul 2030
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior radiation therapy to the target areas;
Other
- Inability to undergo a MRI exam
Who the study is looking for
- Patients with T2-T3N0M0 unifocal bladder cancer of any histologic subtype except squamous cell carcinoma or adenocarcinoma (Janopaul-Naylor et al., 2021) treated the maximal TURBT and able to tolerate concurrent chemoradiotherapy. Selected patients with high risk of common iliac involvement (T4 disease and/or limited N+ disease and/or LVSI+ status) able to receive the following treatment may be included as well. Additional criteria include:
- Karnofsky performance status \> 70 with medical condition not contraindicating treatment with radical intent including maximal TURBT and concomitant chemotherapy;
- WBC equal or greater than 3500 mm3; platelet count equal or greater than 135000 mm3; hemoglobin equal or greater than 10 gr/L; BUN equal or less than 20; serum creatinine equal or less than 2.0.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.