NCT07027254Recruiting
PETAL Trial: Impact of Gallium-68 Pentixafor PET-CT on Surgical Outcomes in Primary Aldosteronism
A Randomized Controlled Trial to Evaluate the Effect of Gallium-68 Pentixafor PET-CT on Surgical Outcomes in Patients With Primary Aldosteronism (The PETAL Trial)
Source: ClinicalTrials.gov · Last updated 18 Jun 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study is a randomized controlled trial to assess the clinical utility of gallium-68 pentixafor PET/CT in the management of primary aldosteronism (PA). We aim to evaluate whether the addition of 68Ga-pentixafor PET/CT to standard adrenal venous sampling (AVS) improves surgical outcomes in patients with unilateral PA.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 90 (estimated)
- First submitted
- 4 Jun 2025
- Start date
- 25 Jun 2025
- Primary completion date
- 1 Jun 2027
- Lead sponsor
- Seoul National University Hospital
- Diseases
- High blood pressure
- NCT number
- NCT07027254
What you commit to
- Study type: Interventional
- Planned participants: 90
- From 25 Jun 2025 to the primary completion date, 1 Jun 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Individuals who refuse to undergo surgery
- Individuals who refuse or experience adverse effects from dexamethasone premedication required for 11C-Metomidate PET/CT
Other illness
- Individuals for whom 68Ga-Pentixafor PET/CT, 11C-Metomidate PET/CT, or adrenal venous sampling (AVS) is not feasible or is refused due to underlying conditions
- Individuals with a history of abdominal open surgery or retroperitoneal surgery on the same side as the planned adrenalectomy
Other
- Women who are pregnant, breastfeeding, or may become pregnant
- Any individual deemed unsuitable for the study at the discretion of the investigator
Who the study is looking for
- Age ≥19 years
- Diagnosed with PA per 2016 Endocrine Society guidelines
- Underwent adrenal CT
- Signed informed consent
Age in the registry: 19 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Seoul National University Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Recruiting |
| Samsung Medical Center Coordinator of this site? Confirm its status | Seoul | South Korea | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.