NCT07029373Completed
Plasma Calcitonin Gene-Related Peptide (CGRP) Levels in Patients With Head and Neck Malignancies Undergoing Radiotherapy
A Prospective Clinical Study for Analyzing Plasma Calcitonin Gene-Related Peptide (CGRP) Levels in Patients With Head and Neck Malignancies Undergoing Radiotherapy
Source: ClinicalTrials.gov · Last updated 21 Apr 2026
Brief summary (registry, in English)
This prospective study investigates the dynamic changes in plasma calcitonin gene-related peptide (CGRP) levels during radiotherapy and their association with radiotherapy-related pain in patients with head and neck malignancies.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 23 (actual)
- First submitted
- 1 Jun 2025
- Start date
- 4 Jul 2025
- Primary completion date
- 2 Apr 2026
- Lead sponsor
- West China Hospital
- Diseases
- Head and neck cancer
- NCT number
- NCT07029373
What you commit to
- Study type: Observational
- Participants enrolled: 23
- From 4 Jul 2025 to the primary completion date, 2 Apr 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- History of significant chronic pain prior to radiotherapy (e.g., postherpetic neuralgia, rheumatoid arthritis)
- Presence of uncontrolled hypertension, diabetes, or migraines
- Presence of other active malignancies or major systemic diseases (e.g., severe hepatic or renal dysfunction)
- Currently receiving or recently received treatments that may significantly affect pain perception (e.g., opioids, antidepressants)
- Pregnant or breastfeeding
- Inability to complete follow-up or poor treatment compliance
Who the study is looking for
- Age ≥ 18 years
- Histologically confirmed head and neck malignancy
- Planned to receive definitive or postoperative adjuvant radiotherapy
- Radiotherapy duration ≥ 4 weeks, with irradiation field involving the oral cavity, pharynx, or neck region
- Able and willing to provide written informed consent
- Able to complete pain assessments and blood sample collection
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| West China Hospital，Sichuan University Coordinator of this site? Confirm its status | Chengdu | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.