NCT07030205Recruiting
Resting-state Imaging and OSteoporosiS
Source: ClinicalTrials.gov · Last updated 13 May 2026
Brief summary (registry, in English)
This study will be conducted in 20 postmenopausal healthy volunteers, 20 postmenopausal osteoporotic patients with fracture and 20 postmenopausal osteoporotic women without fracture, in order to compare functional connectivity between brain areas. Participants will complete different questionnaires and tests assessing cognition, quality of life, sleep, physical activity, pain, anxiety and depression. A biological sample will be performed in order to evaluate different markers of bone remodeling. A Resting-state functional magnetic resonance imaging (rs-fMRI) will be realized in order to establish functional connectivity between brain regions.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 66 (estimated)
- First submitted
- 12 Jun 2025
- Start date
- 3 Sept 2025
- Primary completion date
- 1 Dec 2026
- Lead sponsor
- University Hospital, Clermont-Ferrand
- Diseases
- Osteoporosis
- NCT number
- NCT07030205
What you commit to
- Study type: Interventional
- Planned participants: 66
- From 3 Sept 2025 to the primary completion date, 1 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Presence of medical devices (implants or prostheses),
Other
- Presence of pacemaker,
- Incompatibility of the patient with the safety criteria of the medical imaging center for carrying out magnetic resonance experiments at 3 Tesla,
- Contraindications to the realization of MRI without injection such as claustrophobia proven, hearing aid, pacemaker wearers, wearing a brain clip,
- Refusal to be informed in the event of the accidental discovery of an anomaly during the resting state functional magnetic resonance imaging,
- Woman under legal protection or deprived of liberty,
- Refusal to participation
Who the study is looking for
- Women aged 50 or over, with postmenopausal osteoporosis, fractured or not, diagnosed by their rheumatologist,
- Able to give informed consent to participate in the research,
- Affiliation with the French Social Security.
- Women aged 50 or over,
- Bone densitometry performed as part of the protocol, not suggestive of osteoporosis and validated by investigators,
- Matched to patients by age, menopausal status, socio-educational level and manual laterality,
- Able to give informed consent to participate in the research,
- Affiliation with the French Social Security.
- Registration or acceptance of registration in the national register of volunteers participating in Research.
Age in the registry: 50 years to - · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU de Clermont-Ferrand Coordinator of this site? Confirm its status | Clermont-Ferrand | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.