NCT07032545Recruiting
Metabotyping of Broccoli Microgreen in Obese Breast Cancer Survivors
Metabotyping of a Functional Food, Broccoli Microgreen, in Obese Breast Cancer Survivors
Source: ClinicalTrials.gov · Last updated 23 Dec 2025
Brief summary (registry, in English)
Obesity can pose significant challenges to maintaining long-term health in cancer survivors by increasing their risk of cancer coming back. Eating a healthy diet is an important way to help manage weight and improve overall health. Broccoli microgreens (BMG) are young broccoli plants packed with nutrients, and research suggests they may help prevent cancer. Previous studies in mice showed that BMG can improve gut health and metabolism, leading to better health outcomes in obese animals. This study will test whether BMG can be a useful addition to the diet of obese breast cancer (BC) survivors who have a higher risk of their cancer returning. 24 obese BC survivors will be invited to eat one serving (one cup, \~57 gram) of fresh BMG every day for two weeks. This will help understand if people can stick to this diet, how their bodies respond, and whether it affects metabolism and inflammation-two key factors linked to cancer risk. Biological markers such as body fat, glucose and lipids as well as gut bacterial changes will be analyzed to see how BMG affects individual health. This study may help create new diet strategies to improve health, reduce cancer risk, and support long-term recovery in cancer patients who are overweight or obese. In the future, this research could help doctors personalize nutrition plans to better support cancer survivors.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 24 (estimated)
- First submitted
- 10 Jun 2025
- Start date
- 3 Dec 2025
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- University of Maryland, Baltimore
- Diseases
- Obesity, Childhood cancers
- NCT number
- NCT07032545
What you commit to
- Study type: Interventional
- Planned participants: 24
- From 3 Dec 2025 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently taking broccoli extract supplements
Other illness
- Have any contraindications to the proposed nutrition intervention as identified by their medical provider, their designee, or the study team (e.g., GI conditions, medication requirements, pregnancy, breastfeeding, recent history of an eating disorder).
- Allergy or intolerance to cruciferous vegetables
Who the study is looking for
- Female
- Had a diagnosis of breast cancer (Stage I-III)
- 2 to 60 months post-curative treatment (surgery, chemotherapy, and/or radiation)
- BMI \> 30 kg/m² (obese classification)
- Willing to avoid cruciferous vegetables during the study
- Able to sign an IRB-approved consent form
Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Breast Evaluation and Treatment Program, University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center Coordinator of this site? Confirm its status | Baltimore | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.