NCT07033572Recruiting
Hybrid Endoscopic Hemithyroidectomy and Targeted Ablation for Bilateral Papillary Thyroid Carcinoma
Source: ClinicalTrials.gov · Last updated 3 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study evaluates a thyroid-function-preserving alternative to routine total thyroidectomy for bilateral papillary thyroid carcinoma (PTC). Eligible adults undergo remote-access gas-less axillo-breast endoscopic hemithyroidectomy with level VI dissection on the dominant side, followed by ultrasound-guided radiofrequency ablation (RFA) of a ≤7 mm contralateral focus during the same anesthesia. Outcomes include structural-recurrence-free survival, endocrine-function preservation, safety, and quality of life over 24 months.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 13 Jun 2025
- Start date
- 1 Jun 2018
- Primary completion date
- 30 Jun 2026
- Lead sponsor
- Fujian Medical University
- Diseases
- Thyroid cancer
- NCT number
- NCT07033572
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 1 Jun 2018 to the primary completion date, 30 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior neck surgery, prior RFA/ethanol injection, or neck irradiation.
Other
- Extrathyroidal extension, gross nodal or distant metastasis.
- Pregnancy or lactation.
- Serious comorbidities precluding anesthesia or follow-up.
Who the study is looking for
- Age 18-65 years.
- Dominant-side PTC ≤1.5 cm suitable for endoscopic resection.
- Contralateral nodule ≤7 mm located ≥2 mm from posterior capsule.
- No radiologic lymph-node metastasis on contralateral side.
- Written informed consent.
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fujian Medical University Union Hospital Coordinator of this site? Confirm its status | Fuzhou | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.